Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.38 |
| ▸ | POLB | P06746 | 3/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.38 |
| ▸ | PKM | P14618 | 2/20 | 0.38 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.38 |
| ▸ | PTPN7 | P35236 | 1/20 | 0.38 |
| ▸ | BLM | P54132 | 1/20 | 0.38 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 3/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | TP53 | P04637 | 2/20 | 0.33 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.33 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19279453 | 0.92 | KMT2A (0.35) | KMT2APOLBL3MBTL1PKMPTPN1 | |
| SCHEMBL30436759 | 0.87 | MAPT (0.37) | KMT2APOLBMAPTALDH1A1MEN1 | |
| SCHEMBL19468426 | 0.87 | MAPT (0.37) | KMT2APOLBMAPTALDH1A1MEN1 | |
| SCHEMBL432528 | 0.86 | KMT2A (0.40) | KMT2APOLBL3MBTL1PKMPTPN1 | |
| SCHEMBL1653635 | 0.83 | KMT2A (0.38) | KMT2APOLBL3MBTL1PKMPTPN1 | |
| SCHEMBL16281711 | 0.83 | KMT2A (0.38) | KMT2APOLBL3MBTL1PKMPTPN1 | |
| SCHEMBL16398303 | 0.77 | KMT2A (0.36) | KMT2APOLBL3MBTL1PKMPTPN1 | |
| SCHEMBL16269441 | 0.73 | LMNA (0.34) | KMT2APOLBMAPTALDH1A1MEN1 | |
| SCHEMBL10187544 | 0.72 | MEN1 (0.41) | KMT2AL3MBTL1PKMMAPTALDH1A1 | |
| SCHEMBL7684954 | 0.72 | KMT2A (0.56) | KMT2APOLBL3MBTL1PKMPTPN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10375956-B2 | Herbicidally active 2-(substituted-phenyl)-cyclopentane-1,3-dione compounds and derivatives thereof | SYNGENTA LIMITED (GB) | 2019-08-13 | — | — | US | disclosed |
| EP-3004063-B1 | HERBICIDALLY ACTIVE 2-(SUBSTITUTED-PHENYL)-CYCLOPENTANE-1,3-DIONE COMPOUNDS AND DERIVATIVES THEREOF | SYNGENTA LTD (GB) | 2018-07-18 | — | — | EP | disclosed |
| US-20170320863-A1 | HERBICIDAL COMPOUNDS | SYNGENTA PARTICIPATIONS AG (CH) | 2017-11-09 | — | — | US | disclosed |
| US-20170320863-A1 | HERBICIDAL COMPOUNDS | SYNGENTA PARTICIPATIONS AG (CH) | 2017-11-09 | — | — | US | disclosed |
| US-9808003-B2 | Herbicidally active 2-(substituted-phenyl)-cyclopentane-1,3-dione compounds and derivatives thereof | SYNGENTA LIMITED (GB) | 2017-11-07 | — | — | US | disclosed |
| US-9808003-B2 | Herbicidally active 2-(substituted-phenyl)-cyclopentane-1,3-dione compounds and derivatives thereof | SYNGENTA LIMITED (GB) | 2017-11-07 | — | — | US | disclosed |
| US-20170311596-A1 | HERBICIDAL COMPOUNDS | SYNGENTA PARTICIPATIONS AG (CH) | 2017-11-02 | — | — | US | disclosed |
| US-20170311596-A1 | HERBICIDAL COMPOUNDS | SYNGENTA PARTICIPATIONS AG (CH) | 2017-11-02 | — | — | US | disclosed |
| EP-2986593-B1 | HERBICIDALLY ACTIVE 2-(SUBSTITUTED-PHENYL)-CYCLOPENTANE-1,3-DIONE COMPOUNDS AND DERIVATIVES THEREOF | SYNGENTA LTD (GB) | 2017-07-19 | — | — | EP | disclosed |
| US-20160128326-A1 | Herbicidally Active 2-(Substituted-Phenyl)-Cyclopentane-1,3-Dione Compounds and Derivatives Thereof | SYNGENTA LIMITED (GB) | 2016-05-12 | — | — | US | disclosed |
| US-20160081334-A1 | Herbicidally active 2-(substituted-phenyl)-cyclopentane-1,3-dione compounds and derivatives thereof | SYNGENTA LIMITED (GB) | 2016-03-24 | — | — | US | disclosed |
| US-20160081334-A1 | Herbicidally active 2-(substituted-phenyl)-cyclopentane-1,3-dione compounds and derivatives thereof | SYNGENTA LIMITED (GB) | 2016-03-24 | — | — | US | disclosed |
| WO-2014170413-A1 | HERBICIDALLY ACTIVE 2-(SUBSTITUTED-PHENYL)-CYCLOPENTANE-1,3-DIONE COMPOUNDS AND DERIVATIVES THEREOF | SYNGENTA LIMITED (GB) | 2014-10-23 | — | — | WO | disclosed |
| US-8680339-B2 | Herbicides | SYNGENTA LIMITED (GB) | 2014-03-25 | — | — | US | disclosed |
| US-8680339-B2 | Herbicides | SYNGENTA LIMITED (GB) | 2014-03-25 | — | — | US | disclosed |
| US-20120028800-A1 | NOVEL HERBICIDES | SYNGENTA CROP PROTECTION LLC (US) | 2012-02-02 | — | — | US | disclosed |
| US-20120028800-A1 | NOVEL HERBICIDES | SYNGENTA CROP PROTECTION LLC (US) | 2012-02-02 | — | — | US | disclosed |
| WO-2010089210-A1 | NOVEL HERBICIDES | SYNGENTA LIMITED (GB) | 2010-08-12 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160128326-A1 | Herbicidally Active 2-(Substituted-Phenyl)-Cyclopentane-1,3-Dione Compounds and Derivatives Thereof | DDT, HDHD5, CNPY2 | KMT2A 694/4885POLB 3857/4885L3MBTL1 1149/4885 |
| US-20170311596-A1 | HERBICIDAL COMPOUNDS | GLRX3, DHRS9, DDT | KMT2A 1587/4885POLB 4319/4885L3MBTL1 906/4885 |
| US-20170320863-A1 | HERBICIDAL COMPOUNDS | DHRS9, DDT, MTX1 | KMT2A 1247/4885POLB 4375/4885L3MBTL1 1027/4885 |
| US-10375956-B2 | Herbicidally active 2-(substituted-phenyl)-cyclopentane-1,3-dione compounds and derivatives thereof | DDT, HDHD5, CNPY2 | KMT2A 694/4885POLB 3857/4885L3MBTL1 1149/4885 |
| US-20120028800-A1 | NOVEL HERBICIDES | DDT, CYP4X1, CYP1B1 | KMT2A 674/4885POLB 4374/4885L3MBTL1 1453/4885 |
| US-20160081334-A1 | Herbicidally active 2-(substituted-phenyl)-cyclopentane-1,3-dione compounds and derivatives thereof | DDT, DHPS, HPD | KMT2A 1800/4885POLB 3600/4885L3MBTL1 3438/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.