Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | ITGB2 | P05107 | 1/20 | 0.36 |
| ▸ | ICAM1 | P05362 | 1/20 | 0.36 |
| ▸ | ITGAL | P20701 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | P4HB | P07237 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 2/20 | 0.32 |
| ▸ | CRHBP | P24387 | 2/20 | 0.32 |
| ▸ | CRHR2 | Q13324 | 2/20 | 0.32 |
| ▸ | HTT | P42858 | 2/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4923363 | 0.78 | MAPT (0.39) | MAPTKDM4EGAAALDH1A1ITGB2 | |
| SCHEMBL8405592 | 0.78 | ADRA2A (0.46) | MAPTKDM4EGAAALDH1A1ITGB2 | |
| Hydrochloric Acid SCHEMBL18686536 | 0.77 | MAPT (0.42) | MAPTKDM4EGAAALDH1A1ITGB2 | |
| SCHEMBL22827024 | 0.75 | MAPT (0.38) | MAPTKDM4EGAAALDH1A1ITGB2 | |
| SCHEMBL29619656 | 0.75 | MAPT (0.38) | MAPTKDM4EGAAALDH1A1ITGB2 | |
| SCHEMBL25352397 | 0.75 | ALOX5 (0.44) | MAPTKDM4EALDH1A1ITGB2ICAM1 | |
| SCHEMBL30438835 | 0.75 | ALOX5 (0.44) | MAPTKDM4EALDH1A1ITGB2ICAM1 | |
| SCHEMBL2026290 | 0.75 | LMNA (0.38) | MAPTKDM4EALDH1A1ITGB2ICAM1 | |
| SCHEMBL12116986 | 0.75 | ALDH1A1 (0.38) | MAPTKDM4EGAAALDH1A1ITGB2 | |
| SCHEMBL9221553 | 0.75 | MAPT (0.39) | MAPTKDM4EGAAALDH1A1ITGB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012001107-A1 | PIPERIDINE DERIVATIVES AND THEIR USE FOR THE TREATMENT OF METABOLIC DISORDERS | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2012-01-05 | — | — | WO | disclosed |