Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCD | O00767 | 9/20 | 0.54 |
| ▸ | FADS1 | O60427 | 1/20 | 0.54 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.49 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.49 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.49 |
| ▸ | NPBWR1 | P48145 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10188929 | 0.79 | DGAT1 (0.52) | SCDFADS1CYP1A2CYP3A4CYP2C9 | |
| SCHEMBL902542 | 0.76 | PDE7A (0.37) | CYP1A2CYP3A4CYP2C9CYP2C19 | |
| SCHEMBL10189571 | 0.74 | DGAT1 (0.40) | SCDFADS1 | |
| SCHEMBL14972153 | 0.74 | DGAT1 (0.77) | SCDFADS1 | |
| SCHEMBL914575 | 0.73 | SCD (0.80) | SCDFADS1NPBWR1 | |
| SCHEMBL902869 | 0.73 | CAMKK2 (0.37) | CYP3A4CYP2C9 | |
| SCHEMBL901694 | 0.72 | DGAT1 (0.52) | SCDFADS1 | |
| SCHEMBL914427 | 0.71 | SCD (1.00) | SCDFADS1NPBWR1 | |
| SCHEMBL914295 | 0.71 | SCD (1.00) | SCDFADS1NPBWR1 | |
| SCHEMBL10189562 | 0.70 | DGAT1 (0.57) | NPBWR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012044567-A2 | IMIDAZOLE DERIVATIVES | MERCK SHARP & DOHME CORP. (US) | 2012-04-05 | — | — | WO | disclosed |