Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DGAT1 | O75907 | 6/20 | 0.40 |
| ▸ | SOAT1 | P35610 | 2/20 | 0.40 |
| ▸ | KDM1A | O60341 | 3/20 | 0.40 |
| ▸ | MAOB | P27338 | 3/20 | 0.40 |
| ▸ | MAOA | P21397 | 2/20 | 0.40 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.37 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.37 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.37 |
| ▸ | FASN | P49327 | 2/20 | 0.36 |
| ▸ | SCD | O00767 | 2/20 | 0.36 |
| ▸ | FADS1 | O60427 | 1/20 | 0.36 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.35 |
| ▸ | SLC6A9 | P48067 | 1/20 | 0.35 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10188929 | 0.88 | DGAT1 (0.52) | DGAT1SOAT1SCDFADS1KCNH2 | |
| SCHEMBL901694 | 0.81 | DGAT1 (0.52) | DGAT1SOAT1SCDFADS1KCNH2 | |
| SCHEMBL10189113 | 0.77 | DGAT1 (0.64) | DGAT1SOAT1SCD | |
| SCHEMBL10189649 | 0.75 | DGAT1 (0.52) | DGAT1SOAT1SCD | |
| SCHEMBL10381835 | 0.75 | DGAT1 (0.59) | DGAT1KCNH2 | |
| SCHEMBL10189555 | 0.74 | SCD (0.54) | SCDFADS1 | |
| SCHEMBL10189215 | 0.73 | DGAT1 (0.49) | DGAT1SOAT1SCD | |
| SCHEMBL14695340 | 0.71 | GPR119 (0.56) | — | |
| SCHEMBL10189564 | 0.71 | DGAT1 (0.47) | DGAT1SOAT1KCNH2 | |
| SCHEMBL10189574 | 0.69 | DGAT1 (0.61) | DGAT1SOAT1TLR9TLR8TLR7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012044567-A2 | IMIDAZOLE DERIVATIVES | MERCK SHARP & DOHME CORP. (US) | 2012-04-05 | — | — | WO | disclosed |