Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RORC | P51449 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | GRIK1 | P39086 | 1/20 | 0.36 |
| ▸ | GRIK2 | Q13002 | 1/20 | 0.36 |
| ▸ | PER2 | O15055 | 9/20 | 0.35 |
| ▸ | CRY1 | Q16526 | 9/20 | 0.35 |
| ▸ | CRY2 | Q49AN0 | 9/20 | 0.35 |
| ▸ | ESR1 | P03372 | 2/20 | 0.35 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.33 |
| ▸ | PKM | P14618 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | PFKFB2 | O60825 | 1/20 | 0.33 |
| ▸ | NSD2 | O96028 | 1/20 | 0.33 |
| ▸ | PFKFB1 | P16118 | 1/20 | 0.33 |
| ▸ | PFKFB3 | Q16875 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10095616 | 0.83 | CHRNA7 (0.43) | RORCKDM4EALDH1A1MAPTMAPK1 | |
| SCHEMBL10095619 | 0.82 | PTGER4 (0.41) | RORCKDM4EALDH1A1HSD17B10MAPT | |
| SCHEMBL10095617 | 0.82 | CYP11B2 (0.44) | RORCKDM4EMAPTMAPK1L3MBTL1 | |
| SCHEMBL10095620 | 0.82 | PGR (0.44) | KDM4EMAPTMAPK1L3MBTL1PER2 | |
| SCHEMBL10095618 | 0.82 | KDM4E (0.41) | KDM4EALDH1A1HSD17B10MAPTMAPK1 | |
| SCHEMBL10095578 | 0.70 | CA12 (0.52) | KDM4EALDH1A1HSD17B10MAPTMAPK1 | |
| SCHEMBL10097253 | 0.69 | GRIK2 (0.71) | KDM4EALDH1A1MAPTMAPK1L3MBTL1 | |
| SCHEMBL10095610 | 0.69 | S1PR1 (0.42) | RORCKDM4EALDH1A1HSD17B10MAPT | |
| SCHEMBL10097247 | 0.69 | PGR (0.44) | ALDH1A1GRIK1GRIK2PFKFB2NSD2 | |
| SCHEMBL10095574 | 0.69 | KIF11 (0.45) | KDM4EALDH1A1HSD17B10MAPTMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120009142-A1 | METHODS FOR TREATING HEPATITIS C | PTC THERAPEUTICS, INC. (US) | 2012-01-12 | — | — | US | disclosed |
| US-20120009142-A1 | METHODS FOR TREATING HEPATITIS C | PTC THERAPEUTICS, INC. (US) | 2012-01-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120009142-A1 | METHODS FOR TREATING HEPATITIS C | OAT, HAVCR2, HCCS | RORC 942/4885KDM4E 3703/4885ALDH1A1 591/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.