Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCL2A1 | Q16548 | 1/20 | 0.49 |
| ▸ | TGM2 | P21980 | 2/20 | 0.43 |
| ▸ | BRD4 | O60885 | 2/20 | 0.42 |
| ▸ | APP | P05067 | 3/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | SNCA | P37840 | 1/20 | 0.39 |
| ▸ | BRCA1 | P38398 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | POLQ | O75417 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10362074 | 0.84 | ALDH1A1 (0.48) | TGM2APPMAPTSMN1; SMN2KMT2A | |
| SCHEMBL7267715 | 0.82 | ALDH1A1 (0.46) | TGM2GAAMAPTPKMSMN1; SMN2 | |
| SCHEMBL587718 | 0.82 | ALDH5A1 (0.45) | TGM2APPGAAMAPTSMN1; SMN2 | |
| SCHEMBL10194675 | 0.81 | BCL2A1 (0.49) | BCL2A1TGM2CYP1A2CYP2C19MAPT | |
| SCHEMBL27083988 | 0.80 | BCL2A1 (0.51) | BCL2A1TGM2APPCYP1A2CYP2C19 | |
| SCHEMBL319608 | 0.80 | KMT2A (0.46) | MAPTPKMSMN1; SMN2KMT2AKDM4E | |
| SCHEMBL9133281 | 0.79 | NPC1 (0.47) | TGM2MAPTSMN1; SMN2KMT2AKDM4E | |
| SCHEMBL8446378 | 0.79 | CYP2A6 (0.53) | TGM2SMN1; SMN2KDM4ENPC1RAB9A | |
| Water SCHEMBL11228979 | 0.79 | TGM2 (0.40) | BCL2A1TGM2BRD4MAPTSMN1; SMN2 | |
| Water SCHEMBL11223771 | 0.79 | TGM2 (0.40) | BCL2A1TGM2BRD4MAPTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8895551-B2 | Acrylamide compounds and the use thereof | SHIONOGI & CO., LTD. (JP) | 2014-11-25 | — | — | US | disclosed |
| US-20120022069-A1 | ACRYLAMIDE COMPOUNDS AND THE USE THEREOF | SHIONOGI & CO., LTD. (JP) | 2012-01-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120022069-A1 | ACRYLAMIDE COMPOUNDS AND THE USE THEREOF | TRPA1, TRPV1, CACNA1B | BCL2A1 707/4885TGM2 3257/4885BRD4 3677/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.