SCHEMBL10195757

SCHEMBL10195757

Cc1ccc(NC(=O)C2CCNCC2)cc1C

nearest known ligand 0.75

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 2/20 0.59
KMT2A Q03164 2/20 0.59
NPC1 O15118 4/20 0.58
RAB9A P51151 4/20 0.58
GAA P10253 3/20 0.57
ULK1 O75385 1/20 0.54
ALDH1A1 P00352 2/20 0.53
MAOB P27338 1/20 0.52
POLB P06746 1/20 0.51
F13A1 P00488 1/20 0.51
TGM2 P21980 1/20 0.51
NAMPT P43490 1/20 0.50
NPSR1 Q6W5P4 1/20 0.50
CYP3A4 P08684 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12764173 0.90 MEN1 (0.69) MEN1KMT2ANPC1RAB9AGAA
SCHEMBL12764175 0.87 RAB9A (0.74) MEN1KMT2ANPC1RAB9AGAA
Hydrochloric Acid SCHEMBL23246103 0.87 ULK1 (0.51) MEN1KMT2ANPC1RAB9AGAA
SCHEMBL24060059 0.86 RAB9A (0.72) MEN1KMT2ANPC1RAB9AGAA
SCHEMBL13144615 0.84 ALDH1A1 (0.58) MEN1KMT2AULK1ALDH1A1POLB
SCHEMBL10197819 0.83 ALDH1A1 (0.60) MEN1KMT2ANPC1RAB9AGAA
SCHEMBL13707510 0.81 SIRT2 (0.56) MEN1KMT2ANPC1RAB9AGAA
SCHEMBL259383 0.80 NPSR1 (0.78) MEN1KMT2ANPC1RAB9AGAA
SCHEMBL20037532 0.79 ULK1 (0.52) NPC1RAB9AULK1ALDH1A1NAMPT
SCHEMBL10151574 0.79 SNCA (0.58) MEN1KMT2ANPC1RAB9AGAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2023113457-A1 NOVEL COMPOUND FOR DEGRADING TARGET PROTEIN OR POLYPEPTIDE BY USING POLYUBIQUITINATION (주)프레이저테라퓨틱스 2023-06-22 WO disclosed
WO-2012006104-A2 COMPOUNDS AND METHODS FOR TREATING TUBERCULOSIS INFECTION Academia Sinica, Taiwan (TW) 2012-01-12 WO disclosed