SCHEMBL101963

SCHEMBL101963

O=S(=O)(Cl)c1cccc(Br)c1

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.52
HSD17B10 Q99714 1/20 0.52
TDP1 Q9NUW8 1/20 0.52
WDR5 P61964 1/20 0.45
ATM Q13315 1/20 0.45
MMP2 P08253 2/20 0.44
FLT1 P17948 1/20 0.43
FLT4 P35916 1/20 0.43
KDR P35968 1/20 0.43
PGR P06401 2/20 0.42
MBTD1 Q05BQ5 1/20 0.41
L3MBTL3 Q96JM7 1/20 0.41
BRD4 O60885 1/20 0.41
HSD17B2 P37059 1/20 0.41
EDNRB P24530 2/20 0.41
EDNRA P25101 2/20 0.41
CA1 P00915 1/20 0.40
CA2 P00918 1/20 0.40
CA5A P35218 1/20 0.40
CA9 Q16790 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21384877 0.92 ALDH1A1 (0.50) ALDH1A1HSD17B10TDP1WDR5ATM
1,4-Dimethoxybenzene SCHEMBL27865602 0.84 PGR (0.44) ALDH1A1HSD17B10TDP1PGR
SCHEMBL56599 0.83 ALDH1A1 (0.65) ALDH1A1HSD17B10TDP1PGRCA1
SCHEMBL31391247 0.81 LMNA (0.54) ALDH1A1WDR5ATMMMP2PGR
SCHEMBL3679487 0.81 LMNA (0.54) ALDH1A1WDR5ATMMMP2PGR
SCHEMBL31668877 0.81 LMNA (0.54) ALDH1A1WDR5ATMMMP2PGR
SCHEMBL27365264 0.80 ALDH1A1 (0.46) ALDH1A1TDP1WDR5ATMMMP2
SCHEMBL3035464 0.79 ATM (0.46) ALDH1A1WDR5ATMMMP2FLT1
Methane SCHEMBL28512984 0.78 ALDH1A1 (0.44) ALDH1A1TDP1WDR5ATMMMP2
SCHEMBL10633314 0.78 ALDH1A1 (0.51) ALDH1A1HSD17B10TDP1PGRCA2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1605 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-122036597-A Compound, preparation method thereof, electrolyte and lithium ion battery 蓝固(淄博)新能源科技有限公司 2026-05-15 CN claimed
CN-119425423-A Positively charged composite membrane and preparation method and application thereof 中国石油化工股份有限公司 2025-02-14 CN claimed
CN-119390741-A Morroniside derivative with antioxidant activity and synthesis method thereof 黑龙江中医药大学 2025-02-07 CN claimed
CN-111472019-A Synthesis method of N-sulfonyl azole compound 安阳师范学院 2020-07-31 CN claimed
CN-106674200-A Compound containing L-prolinamide fragment, and preparation method and application thereof 西安交通大学 2017-05-17 CN claimed
CN-104678028-A Pretreatment and detection method for biogen amine neurotransmitter and detection kit INST PHARM & TOXICOLOGY AMMS 2015-06-03 CN claimed
EP-1377589-B1 OXAZOLYL-PYRAZOLE DERIVATIVES AS KINASE INHIBITORS PHARMACIA ITALIA SPA (IT) 2005-09-07 EP claimed
CN-119320374-B Method for synthesizing 3-sulfonyl substituted chromone derivative by photocatalysis JIANG University OF TECHNOLOGY (CN) 2026-05-26 CN disclosed
US-12630548-B2 Azetidine derivatives for the treatment of integrin associated diseases THE UNIVERSITY OF NOTTINGHAM (GB) 2026-05-19 US disclosed
CN-122036597-A Compound, preparation method thereof, electrolyte and lithium ion battery 蓝固(淄博)新能源科技有限公司 2026-05-15 CN disclosed
WO-2026087635-A1 DIHYDRO BENZOXAZINE DERIVATIVES F. HOFFMANN-LA ROCHE AG (CH) 2026-04-30 WO disclosed
US-20260092053-A1 KHK INHIBITORS GILEAD SCIENCES INC (US) 2026-04-02 US disclosed
EP-4713096-A1 CDK INHIBITOR COMPOUNDS Aleksia Therapeutics, Inc. (US) 2026-03-25 EP disclosed
US-4507315-A Hypoglycaemic and hypolipidaemic benzamide substituted (1H-) imidazole derivatives and compositions MAY & BAKER LIMITED (GB) 1985-03-26 US disclosed
US-4167567-A Antihypertensive 4-aminoquinolines THE UPJOHN COMPANY (US) 1979-09-11 US disclosed
US-4065618-A Process for 3-H-3-cephem esters ELI LILLY AND COMPANY (US) 1977-12-27 US disclosed
US-4065621-A Process for 3-alkyl and 3-phenyl cephalosporins ELI LILLY AND COMPANY (US) 1977-12-27 US disclosed
US-4013651-A 3-SUBSTITUTED AMINO-CEPHALOSPORINS ELI LILLY AND COMPANY (US) 1977-03-22 US disclosed
US-3992377-A 3-Thio-substituted cephalosporin antibiotics ELI LILLY AND COMPANY (US) 1976-11-16 US disclosed
US-3985737-A ANTIBACTERIAL AGENTS ELI LILLY AND COMPANY (US) 1976-10-12 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260092053-A1 KHK INHIBITORS KHK, SLC5A2, HK1 ALDH1A1 700/4885HSD17B10 677/4885TDP1 3648/4885
US-12630548-B2 Azetidine derivatives for the treatment of integrin associated diseases ITGA2, ITGB2, ITGB1 ALDH1A1 814/4885HSD17B10 3114/4885TDP1 4504/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.