SCHEMBL3679487

SCHEMBL3679487

O=S(=O)(c1cccc(Br)c1)c1cccc(Br)c1

nearest known ligand 0.54

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 2/20 0.54
HTR6 P50406 1/20 0.48
ATM Q13315 1/20 0.47
KMT2A Q03164 2/20 0.47
GAA P10253 1/20 0.47
HTT P42858 1/20 0.47
MMP2 P08253 1/20 0.46
FEN1 P39748 1/20 0.45
PGR P06401 1/20 0.45
C1S P09871 1/20 0.44
SMN1; SMN2 Q16637 3/20 0.44
ALDH1A1 P00352 3/20 0.44
TSHR P16473 1/20 0.44
KDM4E B2RXH2 1/20 0.44
MEN1 O00255 1/20 0.44
NPC1 O15118 1/20 0.44
MAPT P10636 1/20 0.44
HPGD P15428 1/20 0.44
RAB9A P51151 1/20 0.44
MBTD1 Q05BQ5 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31391247 1.00 LMNA (0.54) LMNAHTR6ATMKMT2AGAA
SCHEMBL31668877 1.00 LMNA (0.54) LMNAHTR6ATMKMT2AGAA
SCHEMBL3831593 0.93 HTR6 (0.61) LMNAHTR6ATMKMT2AMMP2
SCHEMBL29799515 0.93 LMNA (0.48) LMNAHTR6ATMKMT2AGAA
SCHEMBL29945255 0.93 HTR6 (0.61) LMNAHTR6ATMKMT2AMMP2
SCHEMBL15239367 0.91 ALDH1A1 (0.51) LMNAHTR6ATMKMT2AGAA
SCHEMBL9460224 0.88 HTR2C (0.50) LMNAHTR6ATMMMP2
SCHEMBL9460854 0.86 ALDH1A1 (0.59) LMNAKMT2AGAAHTTSMN1; SMN2
SCHEMBL9459975 0.86 EGFR (0.48) LMNAHTR6KMT2AGAAHTT
SCHEMBL9360176 0.84 LMNA (0.52) LMNAKMT2APGRSMN1; SMN2MEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 36 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260015335-A1 AMINE-SUBSTITUTED FLUORESCENT COMPOUNDS HUGHES HOWARD MED INST (US) 2026-01-15 US disclosed
US-20260001857-A1 FLUORINATED FLUORESCENT COMPOUNDS HUGHES HOWARD MED INST (US) 2026-01-01 US disclosed
US-20250282744-A1 RED-SHIFTED FLUOROPHORES HOWARD HUGHES MEDICAL INSTITUTE 2025-09-11 US disclosed
US-12344594-B2 Red-shifted fluorophores HOWARD HUGHES MEDICAL INSTITUTE (US) 2025-07-01 US disclosed
US-20210171490-A1 RED-SHIFTED FLUOROPHORES HOWARD HUGHES MEDICAL INSTITUTE 2021-06-10 US disclosed
EP-3533602-A1 LAMINATE FILM, ELECTRONIC DEVICE MEMBER, AND ELECTRONIC DEVICE Lintec Corporation (JP) 2019-09-04 EP disclosed
US-20190232611-A1 LAMINATE FILM, ELECTRONIC DEVICE MEMBER, AND ELECTRONIC DEVICE LINTEC CORPORATION (JP) 2019-08-01 US disclosed
EP-3385409-A1 ELECTROLYTIC SULPHURIC ACID BATH AND METHOD FOR TIN ELECTROREFINIG Estanos y Soldaduras Senra, S.L.U. (ES) 2018-10-10 EP disclosed
EP-2951226-A1 TRIBLOCK COPOLYMER, METHOD FOR ITS FORMATION, AND COMPATIBILIZED COMPOSITIONS COMPRISING IT SABIC Global Technologies B.V. (NL) 2015-12-09 EP disclosed
EP-2822998-A1 COMPATIBILIZED COMPOSITION, METHOD FOR THE FORMATION THEREOF, AND ARTICLE COMPRISING SAME SABIC Innovative Plastics IP B.V. (NL) 2015-01-14 EP disclosed
US-20030173547-A1 Halogenated aromatic compound, (co)polymer thereof, and proton-conductive membrane comprising same JSR CORPORATION (JP) 2003-09-18 US disclosed
EP-1329444-A1 Halogenated aromatic compound, (co)polymer thereof, and proton-conductive membrane comprising same JSR Corporation (JP) 2003-07-23 EP disclosed
US-20020177656-A1 Monomer containing electron-withdrawing group and electron-donative group, and copolymer and proton-conductive membrane comprising same JSR CORPORATION (JP) 2002-11-28 US disclosed
US-20020172850-A1 Polymer electrolyte membrane and solid polymer electrolyte fuel cell using same HONDA GIKEN KOGYO KABUSHIKI KAISHA, JSR CORPORATION 2002-11-21 US disclosed
CN-1379009-A Monomer containing electron drawing group and electron donating group and polymer and proton conductive membrane containing same JSR CORP (JP) 2002-11-13 CN disclosed
EP-1245554-A1 Monomer containing electron-withdrawing group and electron-donative group, and copolymer and proton-conductive membrane comprising same JSR Corporation (JP) 2002-10-02 EP disclosed
EP-1242503-A1 METHOD FOR ISOLATING DIHYDROXYBIPHENYL POLYETHERSULFONES GENERAL ELECTRIC COMPANY (US) 2002-09-25 EP disclosed
WO-2001038422-A1 METHOD FOR ISOLATING DIHYDROXYBIPHENYL POLYETHERSULFONES GENERAL ELECTRIC COMPANY (US) 2001-05-31 WO disclosed
US-6197924-B1 CRYSTALLIZATION, COOLING; BY-PRODUCT REMOVAL GENERAL ELECTRIC COMPANY 2001-03-06 US disclosed
US-4287366-A BY OXIDATION OF THE CORRESPONDING SULFIDE OR SULFOXIDE WITH HYDROGEN PEROXIDE IN THE PRESENCE OF AN ALKALI METAL HYDROXIDE MITSUI TOATSU CHEMICALS, INC. (JP) 1981-09-01 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12344594-B2 Red-shifted fluorophores TFEB, DDX21, CDC73 LMNA 314/4885HTR6 2157/4885ATM 3401/4885
US-20250282744-A1 RED-SHIFTED FLUOROPHORES TFEB, DDX21, CDC73 LMNA 315/4885HTR6 2158/4885ATM 3397/4885
US-20260001857-A1 FLUORINATED FLUORESCENT COMPOUNDS MSN, CHN2, EFHD2 LMNA 742/4885HTR6 176/4885ATM 3443/4885
US-20260015335-A1 AMINE-SUBSTITUTED FLUORESCENT COMPOUNDS AOC2, H1-2, CHAT LMNA 1019/4885HTR6 113/4885ATM 1980/4885
US-20210171490-A1 RED-SHIFTED FLUOROPHORES TFEB, DDX21, CDC73 LMNA 314/4885HTR6 2157/4885ATM 3401/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.