SCHEMBL10199005

SCHEMBL10199005

CC=CC(=O)Nc1ccccc1C(=O)O

nearest known ligand 0.61

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ TRPM2 O94759 2/20 0.61
▸ LTB4R Q15722 1/20 0.61
▸ TRPA1 O75762 8/20 0.60
▸ TRPM8 Q7Z2W7 6/20 0.60
▸ KMT2A Q03164 5/20 0.59
▸ SMN1; SMN2 Q16637 4/20 0.59
▸ MEN1 O00255 4/20 0.59
▸ NPC1 O15118 3/20 0.59
▸ RAB9A P51151 3/20 0.59
▸ MAPT P10636 2/20 0.59
▸ KDM4E B2RXH2 3/20 0.58
▸ APEX1 P27695 2/20 0.58
▸ RECQL P46063 2/20 0.58
▸ POLB P06746 1/20 0.58
▸ TDP1 Q9NUW8 1/20 0.58
▸ L3MBTL1 Q9Y468 1/20 0.58
▸ MASP2 O00187 1/20 0.57
▸ HTT P42858 2/20 0.56
▸ ALDH1A1 P00352 3/20 0.56
▸ HPGD P15428 3/20 0.56

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14206787 1.00 TRPM2 (0.61) TRPM2LTB4RTRPA1TRPM8KMT2A
SCHEMBL25054067 0.89 TRPA1 (0.59) TRPM2LTB4RTRPA1TRPM8KMT2A
SCHEMBL10936745 0.84 ALDH1A1 (0.76) TRPM2LTB4RTRPA1TRPM8KMT2A
SCHEMBL10199018 0.84 ALDH1A1 (0.76) TRPM2LTB4RTRPA1TRPM8KMT2A
SCHEMBL24594132 0.83 SMN1; SMN2 (0.75) KMT2ASMN1; SMN2MAPTKDM4EPOLB
SCHEMBL20342066 0.83 ALDH1A1 (0.50) TRPM2LTB4RTRPA1TRPM8KMT2A
SCHEMBL294403 0.81 TRPM2 (0.83) TRPM2LTB4RTRPA1TRPM8KMT2A
SCHEMBL294402 0.81 TRPM2 (0.83) TRPM2LTB4RTRPA1TRPM8KMT2A
SCHEMBL18362785 0.81 SMN1; SMN2 (0.58) TRPA1TRPM8KMT2ASMN1; SMN2MEN1
SCHEMBL8635715 0.80 TRPA1 (0.78) TRPM2LTB4RTRPA1TRPM8KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240082457-A1 HARD TISSUE REPAIR ADHESIVE COMPOSITION AND HARD TISSUE REPAIR KIT THEREOF Jiaxing Jingyin Biotechnology Co., Ltd. (CN) 2024-03-14 — — US disclosed
US-20240016973-A1 ADHESIVE COMPOSITION FOR HARD TISSUE REPAIR Jiaxing Jingyin Biotechnology Co., Ltd. (CN) 2024-01-18 — — US disclosed
CN-113768936-B Application of evodiamine derivative in preparation of medicine for treating superficial fungal infection 南华大学 2023-04-14 — — CN disclosed
CN-113768936-A Application of evodiamine derivative in preparation of medicine for treating superficial fungal infection 南华大学 2021-12-10 — — CN disclosed
US-8115006-B2 Process for producing anthranilamide compound ISHIHARA SANGYO KAISHA, LTD. (JP) 2012-02-14 — — US disclosed
US-20100063293-A1 PROCESS FOR PRODUCING ANTHRANILAMIDE COMPOUND ISHIHARA SANGYO KAISHA ,LTD. (JP) 2010-03-11 — — US disclosed
US-7361785-B2 Compound protecting against ultraviolet rays LEAD CHEMICAL CO., LTD. (JP) 2008-04-22 — — US disclosed
US-7361785-B2 Compound protecting against ultraviolet rays LEAD CHEMICAL CO., LTD. (JP) 2008-04-22 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100063293-A1 PROCESS FOR PRODUCING ANTHRANILAMIDE COMPOUND NAAA, AAAS, AADAC TRPM2 3383/4885LTB4R 3401/4885TRPA1 1465/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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