SCHEMBL10205409

SCHEMBL10205409

Cc1cnccc1-c1ccccn1

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP2A6 P11509 1/20 0.48
KDM4E B2RXH2 6/20 0.48
LMNA P02545 3/20 0.48
METAP1 P53582 2/20 0.48
CCR1 P32246 2/20 0.48
CCR5 P51681 2/20 0.48
CCR8 P51685 2/20 0.48
CYP1A2 P05177 1/20 0.48
POLB P06746 1/20 0.48
BLM P54132 1/20 0.48
HIF1A Q16665 1/20 0.48
DOHH Q9BU89 1/20 0.48
P4HTM Q9NXG6 1/20 0.48
NPC1 O15118 5/20 0.46
PRKCI P41743 1/20 0.45
GRM4 Q14833 1/20 0.44
TDO2 P48775 1/20 0.43
CYP19A1 P11511 1/20 0.43
METAP2 P50579 1/20 0.42
CYP46A1 Q9Y6A2 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5142866 0.85 CYP2A6 (0.48) CYP2A6KDM4ELMNAMETAP1CCR1
SCHEMBL39129 0.79 NPC1 (0.59) KDM4ELMNAMETAP1CCR1CCR5
SCHEMBL30229669 0.79 NPC1 (0.59) KDM4ELMNAMETAP1CCR1CCR5
SCHEMBL30427456 0.79 NPC1 (0.59) KDM4ELMNAMETAP1CCR1CCR5
SCHEMBL12854083 0.78 KDM4E (0.50) CYP2A6KDM4ELMNAMETAP1CCR1
SCHEMBL13798940 0.78 PRKCI (0.46) CYP2A6KDM4ELMNAMETAP1CCR1
SCHEMBL3714209 0.78 NPC1 (0.57) KDM4ELMNAMETAP1CCR1CCR5
SCHEMBL23598962 0.77 CYP2A6 (0.48) CYP2A6KDM4ELMNAMETAP1CCR1
SCHEMBL17180121 0.77 CYP2A6 (0.48) CYP2A6KDM4ELMNAMETAP1CCR1
SCHEMBL16897143 0.77 CYP2A6 (0.48) CYP2A6KDM4ELMNAMETAP1CCR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 97 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11825734-B2 Organic electroluminescent materials and devices UNIVERSAL DISPLAY CORPORATION (US) 2023-11-21 US disclosed
US-11818932-B2 Organic light-emitting device SAMSUNG DISPLAY CO., LTD. (KR) 2023-11-14 US disclosed
EP-4225006-A2 ORGANIC LIGHT-EMITTING DEVICE Samsung Display Co., Ltd. (KR) 2023-08-09 EP disclosed
US-11696496-B2 Organic light-emitting device SAMSUNG DISPLAY CO., LTD. (KR) 2023-07-04 US disclosed
US-11678498-B2 Organic light-emitting device SAMSUNG DISPLAY CO., LTD. (KR) 2023-06-13 US disclosed
EP-3246963-B1 ORGANIC LIGHT-EMITTING DEVICE SAMSUNG DISPLAY CO LTD (KR) 2023-05-31 EP disclosed
US-11653563-B2 Organic light-emitting device SAMSUNG DISPLAY CO., LTD. (KR) 2023-05-16 US disclosed
US-11617290-B2 Organic light-emitting device SAMSUNG DISPLAY CO., LTD. (KR) 2023-03-28 US disclosed
US-11329230-B2 Organic light-emitting device SAMSUNG DISPLAY CO., LTD. (KR) 2022-05-10 US disclosed
US-11316117-B2 Organometallic compound and organic light-emitting device including the same SAMSUNG DISPLAY CO., LTD. (KR) 2022-04-26 US disclosed
US-20170069847-A1 CONDENSED CYCLIC COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE INCLUDING THE SAME Research & Business Foundation Sungkyunkwan University (KR) 2017-03-09 US disclosed
US-20170069847-A1 CONDENSED CYCLIC COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE INCLUDING THE SAME Research & Business Foundation Sungkyunkwan University (KR) 2017-03-09 US disclosed
US-20170054085-A1 ORGANIC LIGHT-EMITTING DEVICE SAMSUNG DISPLAY CO., LTD. (KR) 2017-02-23 US disclosed
US-20170054085-A1 ORGANIC LIGHT-EMITTING DEVICE SAMSUNG DISPLAY CO., LTD. (KR) 2017-02-23 US disclosed
US-20160322579-A1 ORGANIC LIGHT-EMITTING DEVICE SAMSUNG DISPLAY CO., LTD. (KR) 2016-11-03 US disclosed
US-20160293848-A1 CONDENSED-CYCLIC COMPOUND AND ORGANIC LIGHT EMITTING DEVICE INCLUDING THE SAME SAMSUNG DISPLAY CO., LTD. (KR) 2016-10-06 US disclosed
US-20160293845-A1 ORGANIC LIGHT-EMITTING DEVICE SAMSUNG DISPLAY CO., LTD. (KR) 2016-10-06 US disclosed
US-20160285011-A1 CONDENSED CYCLIC COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE COMPRISING THE SAME SAMSUNG DISPLAY CO., LTD. (KR) 2016-09-29 US disclosed
US-20160272621-A1 GSK-3 INHIBITORS BRISTOL-MYERS SQUIBB COMPANY (US) 2016-09-22 US disclosed
US-8101774-B2 Ester derivatives and medicinal use thereof JAPAN TOBACCO INC. (JP) 2012-01-24 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11329230-B2 Organic light-emitting device EML4, SUN2, TRPA1 CYP2A6 1675/4885KDM4E 2540/4885LMNA 2238/4885
US-11825734-B2 Organic electroluminescent materials and devices OCIAD2, OCIAD1, OSBP CYP2A6 1611/4885KDM4E 3905/4885LMNA 3477/4885
US-20160293848-A1 CONDENSED-CYCLIC COMPOUND AND ORGANIC LIGHT EMITTING DEVICE INCLUDING THE SAME CRY1, CRY2, CCNE2 CYP2A6 2249/4885KDM4E 3752/4885LMNA 1208/4885
US-20160285011-A1 CONDENSED CYCLIC COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE COMPRISING THE SAME CCNA1, CCNT1, CCNE2 CYP2A6 1507/4885KDM4E 4266/4885LMNA 642/4885
US-20170069847-A1 CONDENSED CYCLIC COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE INCLUDING THE SAME CRY1, CRY2, CCNE2 CYP2A6 2041/4885KDM4E 3395/4885LMNA 1574/4885
US-11316117-B2 Organometallic compound and organic light-emitting device including the same OCIAD1, L3MBTL1, OCIAD2 CYP2A6 2875/4885KDM4E 3548/4885LMNA 427/4885
US-20160272621-A1 GSK-3 INHIBITORS GSK3B, GSK3A, GSKIP CYP2A6 2029/4885KDM4E 2680/4885LMNA 1497/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.