SCHEMBL528252

SCHEMBL528252

O=[N+]([O-])c1ccccc1C1COCO1

nearest known ligand 0.39

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
MAPT P10636 2/20 0.39
KDM4E B2RXH2 2/20 0.39
L3MBTL1 Q9Y468 2/20 0.39
MEN1 O00255 1/20 0.39
GAA P10253 1/20 0.39
HTT P42858 1/20 0.39
KMT2A Q03164 1/20 0.39
ALDH1A1 P00352 3/20 0.39
TSHR P16473 1/20 0.39
CUL4A Q13619 1/20 0.38
HSD17B10 Q99714 1/20 0.38
DNMT3B Q9UBC3 4/20 0.37
PKM P14618 1/20 0.37
TDP1 Q9NUW8 2/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30886752 1.00 MAPT (0.39) MAPTKDM4EL3MBTL1MEN1GAA
SCHEMBL1021883 0.88 MEN1 (0.44) MAPTKDM4EL3MBTL1MEN1GAA
SCHEMBL30844063 0.88 MEN1 (0.44) MAPTKDM4EL3MBTL1MEN1GAA
SCHEMBL11451379 0.78 GPR35 (0.45) MAPTKDM4EL3MBTL1MEN1GAA
SCHEMBL5486010 0.76 HTT (0.44) MAPTKDM4EL3MBTL1MEN1GAA
SCHEMBL1935386 0.74 KDM4E (0.39) MAPTKDM4EL3MBTL1MEN1GAA
SCHEMBL10819483 0.74 ALDH1A1 (0.43) MAPTKDM4EL3MBTL1MEN1GAA
SCHEMBL18555673 0.73 MEN1 (0.41) MAPTKDM4EL3MBTL1MEN1GAA
SCHEMBL15017705 0.73 TDP1 (0.60) MAPTL3MBTL1MEN1KMT2AALDH1A1
SCHEMBL11743037 0.73 GPR35 (0.49) MAPTKDM4EL3MBTL1MEN1GAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 217 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2016142952-A1 PROCESS FOR PREPARATION OF VILAZODONE AND ITS NOVEL INTERMEDIATES NOSCH LABS PRIVATE LIMITED (IN) 2016-09-15 WO claimed
WO-2008013427-A1 ORGANIC TFTS AND METHOD FOR FABRICATING THE SAME LG CHEM, LTD. (KR) 2008-01-31 WO claimed
WO-2025050647-A1 IONIZABLE CATIONIC LIPID COMPOUNDS AS WELL AS PREPARATION METHOD THEREFOR AND USE THEREOF 晟迪生物医药(苏州)有限公司 2025-03-13 WO disclosed
CN-117986153-A Ionizable cationic lipid compound, and preparation method and application thereof 晟迪生物医药(苏州)有限公司 2024-05-07 CN disclosed
EP-3096369-B1 ORGANIC SOLAR CELL AND METHOD FOR MANUFACTURING SAME LG CHEMICAL LTD (KR) 2020-10-14 EP disclosed
US-20160343956-A1 ORGANIC SOLAR CELL AND METHOD FOR MANUFACTURING SAME LG CHEMICAL LTD (KR) 2016-11-24 US disclosed
EP-3096369-A1 ORGANIC SOLAR CELL AND METHOD FOR MANUFACTURING SAME LG Chem, Ltd. (KR) 2016-11-23 EP disclosed
EP-1373204-B1 HETEROCYCLIC COMPOUNDS JANSSEN PHARMACEUTICALS INC (US) 2016-10-26 EP disclosed
WO-2016142952-A1 PROCESS FOR PREPARATION OF VILAZODONE AND ITS NOVEL INTERMEDIATES NOSCH LABS PRIVATE LIMITED (IN) 2016-09-15 WO disclosed
EP-2563847-B1 MCR DENDRIMERS LEIBNIZ INST FÜR PFLANZENBIOCHEMIE IPB (DE) 2016-04-13 EP disclosed
US-9035070-B2 Process for the preparation of 1-aryl-pyrazol-3-one intermediates useful in the synthesis of sigma receptors inhibitors Esteve Química, S.A. (ES) 2015-05-19 US disclosed
WO-2001074815-A2 PHENYL-SUBSTITUTED IMIDAZOPYRIDINES ORTHO MCNEIL PHARMACEUTICAL, INC. (US) 2001-10-11 WO disclosed
WO-2001074814-A1 PHENYL-SUBSTITUTED INDOLIZINE DERIVATIVES AND THEIR USE AS HISTAMINE H3 LIGANDS ORTHO MCNEIL PHARMACEUTICAL, INC. (US) 2001-10-11 WO disclosed
WO-2001074813-A2 METHOD FOR USING 2- OR 3-ARYL SUBSTITUTED IMIDAZO[1,2-a] PYRIDINES AS H3 ANTAGONISTS ORTHO MCNEIL PHARMACEUTICAL, INC. (US) 2001-10-11 WO disclosed
US-4189611-A USED TO MAKE DIOXOLANES WHICH ENDCAP AND COPOLYMERIZE WITH POLYOXYMETHYLENE GLYCOL MAKING IT HEAT RESISTANT, PRINTING PLATES E. I. DU PONT DE NEMOURS AND COMPANY (US) 1980-02-19 US disclosed
US-4150989-A RELIEF IMAGES, LITHOGRAPHIC PLATES E. I. DU PONT DE NEMOURS AND COMPANY (US) 1979-04-24 US disclosed
US-4111960-A Substituted dioxolanes and photosensitive and degradable polymers useful in imaging E. I. DU PONT DE NEMOURS AND COMPANY (US) 1978-09-05 US disclosed
US-4108839-A RELIEF IMAGING AND LITHOGRAPHY E. I. DU PONT DE NEMOURS AND COMPANY (US) 1978-08-22 US disclosed
US-4075175-A ANIONIC POLYMERIZATION E. I. DU PONT DE NEMOURS AND COMPANY (US) 1978-02-21 US disclosed
US-3991033-A CONTAINING O-NITROPHENYL GROUPS E. I. DU PONT DE NEMOURS & COMPANY (US) 1976-11-09 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20160343956-A1 ORGANIC SOLAR CELL AND METHOD FOR MANUFACTURING SAME DSG1, VCL, SUN2 MAPT 1251/4885KDM4E 1000/4885L3MBTL1 3597/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.