Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 5/20 | 0.62 |
| ▸ | CA2 | P00918 | 5/20 | 0.62 |
| ▸ | PDE3A | Q14432 | 2/20 | 0.62 |
| ▸ | PDE4B | Q07343 | 13/20 | 0.53 |
| ▸ | PDE4A | P27815 | 10/20 | 0.53 |
| ▸ | PDE4C | Q08493 | 10/20 | 0.53 |
| ▸ | PDE4D | Q08499 | 10/20 | 0.53 |
| ▸ | CA12 | O43570 | 3/20 | 0.49 |
| ▸ | CA9 | Q16790 | 3/20 | 0.49 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.48 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.48 |
| ▸ | PDE1A | P54750 | 1/20 | 0.48 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.48 |
| ▸ | PDE7A | Q13946 | 1/20 | 0.48 |
| ▸ | CA4 | P22748 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13983651 | 0.85 | CA1 (0.62) | CA1CA2CA12CA9CA4 | |
| SCHEMBL24244586 | 0.82 | PDE4B (0.67) | PDE3APDE4BPDE4APDE4CPDE4D | |
| SCHEMBL10268396 | 0.77 | CA1 (0.62) | CA1CA2PDE3APDE4BPDE4A | |
| Tavaborole SCHEMBL500016 | 0.77 | CA1 (1.00) | CA1CA2PDE3APDE4BPDE4A | |
| SCHEMBL5583348 | 0.77 | PDE4B (0.69) | CA1CA2PDE3APDE4BPDE4A | |
| SCHEMBL14473060 | 0.77 | CA1 (0.62) | CA1CA2PDE3APDE4BPDE4A | |
| SCHEMBL11886709 | 0.77 | CA1 (0.73) | CA1CA2PDE3APDE4BPDE4A | |
| SCHEMBL499992 | 0.77 | PDE4B (0.69) | CA1CA2PDE3APDE4BPDE4A | |
| An-2718 SCHEMBL500874 | 0.77 | PDE4B (0.69) | CA1CA2PDE3APDE4BPDE4A | |
| SCHEMBL19171231 | 0.77 | CA1 (1.00) | CA1CA2PDE3APDE4BPDE4A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10105377-B2 | Compounds and nail polish | PFIZER INC. (US) | 2018-10-23 | — | — | US | disclosed |
| US-20170216327-A1 | COMPOUNDS AND NAIL POLISH | ANACOR PHARMACEUTICALS, LLC | 2017-08-03 | — | — | US | disclosed |
| US-20170216327-A1 | COMPOUNDS AND NAIL POLISH | ANACOR PHARMACEUTICALS, LLC | 2017-08-03 | — | — | US | disclosed |
| WO-2015171186-A1 | COMPOUNDS AND NAIL POLISH | ANACOR PHARMACEUTICALS, INC. (US) | 2015-11-12 | — | — | WO | disclosed |
| US-20120264714-A1 | BORON-CONTAINING SMALL MOLECULES AS ANTI-INFLAMMATORY AGENTS | ANACOR PHARMACEUTICALS, INC. (US) | 2012-10-18 | — | — | US | disclosed |
| US-8168614-B2 | Boron-containing small molecules as anti-inflammatory agents | ANACOR PHARMACEUTICALS, INC. (US) | 2012-05-01 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10105377-B2 | Compounds and nail polish | KRT18, POLR1C, TUBB2B | CA1 3766/4885CA2 4199/4885PDE3A 4049/4885 |
| US-20120264714-A1 | BORON-CONTAINING SMALL MOLECULES AS ANTI-INFLAMMATORY AGENTS | NFKBIA, LITAF, TNF | CA1 1986/4885CA2 886/4885PDE3A 1851/4885 |
| US-20170216327-A1 | COMPOUNDS AND NAIL POLISH | KRT18, POLR1C, TUBB2B | CA1 3766/4885CA2 4199/4885PDE3A 4049/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.