An-2718

An-2718

SCHEMBL500874

OB1OCc2cc(Cl)ccc21

nearest known ligand 0.69

Full drug profile on Sugi Atlas →

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
PDE4B Q07343 13/20 0.69
PDE4A P27815 10/20 0.69
PDE4C Q08493 10/20 0.69
PDE4D Q08499 10/20 0.69
CA1 P00915 5/20 0.62
CA2 P00918 5/20 0.62
PDE3A Q14432 2/20 0.62
CA12 O43570 2/20 0.49
CA9 Q16790 2/20 0.49
CHRM1 P11229 1/20 0.48
ADRA1A P35348 1/20 0.48
PDE1A P54750 1/20 0.48
PDE3B Q13370 1/20 0.48
PDE7A Q13946 1/20 0.48
CA4 P22748 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
An-2718 SCHEMBL5583381 1.00 PDE4B (0.69) PDE4BPDE4APDE4CPDE4DCA1
SCHEMBL13183439 0.85 CA1 (0.62) PDE4BPDE4APDE4CPDE4DCA1
SCHEMBL564786 0.82 CA1 (0.65) PDE4BPDE4APDE4CPDE4DCA1
SCHEMBL2527365 0.82 PDE4B (1.00) PDE4BPDE4APDE4CPDE4DPDE3A
Methylamine SCHEMBL14735124 0.78 PDE4B (0.92) PDE4BPDE4APDE4CPDE4DPDE3A
SCHEMBL10268396 0.77 CA1 (0.62) PDE4BPDE4APDE4CPDE4DCA1
SCHEMBL14473060 0.77 CA1 (0.62) PDE4BPDE4APDE4CPDE4DCA1
Tavaborole SCHEMBL500016 0.77 CA1 (1.00) PDE4BPDE4APDE4CPDE4DCA1
SCHEMBL10220172 0.77 CA1 (0.62) PDE4BPDE4APDE4CPDE4DCA1
SCHEMBL15186178 0.77 PDE4A (0.44) PDE4BPDE4APDE4CPDE4DCA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 403 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250099495-A1 METHODS OF INHIBITING KLEBSIELLA PNEUMONIAE CARBAPENEMASE-2 CITY UNIVERSITY OF HONG KONG (CN) 2025-03-27 US claimed
US-12098159-B2 Solid forms of substituted benzoxaborole and compositions thereof 5METIS, INC. (US) 2024-09-24 US claimed
US-20230159565-A1 Solid Forms of Substituted Benzoxaborole and Compositions Thereof 5METIS, INC. 2023-05-25 US claimed
US-11560393-B2 Solid forms of substituted benzoxaborole and compositions thereof 5METIS, INC. (US) 2023-01-24 US claimed
EP-4100413-A1 ANTIMICROBIAL COMPOUNDS AND COMPOSITIONS AgroFresh Inc. (US) 2022-12-14 EP claimed
CN-115348965-A Antimicrobial compounds and compositions 阿格洛法士公司 2022-11-15 CN claimed
US-11236115-B2 Solid forms of substituted benzoxaborole and compositions thereof 5METIS, INC. (US) 2022-02-01 US claimed
WO-2021158595-A1 ANTIMICROBIAL COMPOUNDS AND COMPOSITIONS AGROFRESH INC. (US) 2021-08-12 WO claimed
US-20210221827-A1 SOLID FORMS OF SUBSTITUTED BENZOXABOROLE AND COMPOSITIONS THEREOF Boragen, Inc. 2021-07-22 US claimed
US-11066424-B2 Solid forms of substituted benzoxaborole and compositions thereof Boragen, Inc. (US) 2021-07-20 US claimed
US-20160235070-A1 FUNGICIDAL COMPOUNDS AND COMPOSITIONS ALTER DOMUS US LLC 2016-08-18 US claimed
WO-2016079536-A1 ANTIFUNGAL AGENTS F2G LIMITED (GB) 2016-05-26 WO claimed
EP-2810946-B1 1,1'-[1,omega-alkyldiylbis(oxy)]bis[1,3-dihydro-2,1-benzoxaborole as volatile antimicrobial compounds AGROFRESH INC (US) 2016-04-13 EP claimed
WO-2015171186-A1 COMPOUNDS AND NAIL POLISH ANACOR PHARMACEUTICALS, INC. (US) 2015-11-12 WO claimed
US-9138002-B2 Compounds and compositions AGROFRESH INC. (US) 2015-09-22 US claimed
WO-2014197634-A2 ANTIMICROBIAL COMPOUNDS AND COMPOSITIONS DOW AGROSCIENCES LLC (US) 2014-12-11 WO claimed
EP-2810946-A1 1,1'-[1,omega-alkyldiylbis(oxy)]bis[1,3-dihydro-2,1-benzoxaborole as volatile antimicrobial compounds Dow AgroSciences LLC (US) 2014-12-10 EP claimed
US-8889656-B2 Boron-containing small molecules ANACOR PHARMACEUTICALS, INC. (US) 2014-11-18 US claimed
US-20140213551-A1 COMPOUNDS AND COMPOSITIONS DOW AGROSCIENCE LLC (US) 2014-07-31 US claimed
US-8669207-B1 Compounds and compositions DOW AGROSCIENCES, LLC. (US) 2014-03-11 US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (8 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230159565-A1 Solid Forms of Substituted Benzoxaborole and Compositions Thereof BRIX1, CYP2F1, XDH PDE4B 3568/4885PDE4A 4313/4885PDE4C 4347/4885
US-11066424-B2 Solid forms of substituted benzoxaborole and compositions thereof BRIX1, CYP2F1, XDH PDE4B 3568/4885PDE4A 4313/4885PDE4C 4347/4885
US-11560393-B2 Solid forms of substituted benzoxaborole and compositions thereof BRIX1, CYP2F1, XDH PDE4B 3568/4885PDE4A 4313/4885PDE4C 4347/4885
US-11236115-B2 Solid forms of substituted benzoxaborole and compositions thereof BRIX1, CYP2F1, XDH PDE4B 3568/4885PDE4A 4313/4885PDE4C 4347/4885
US-20140213551-A1 COMPOUNDS AND COMPOSITIONS OXA1L, CUL3, CUL2 PDE4B 1316/4885PDE4A 2299/4885PDE4C 1842/4885
US-20210221827-A1 SOLID FORMS OF SUBSTITUTED BENZOXABOROLE AND COMPOSITIONS THEREOF BRIX1, CYP2F1, XDH PDE4B 3568/4885PDE4A 4313/4885PDE4C 4347/4885
US-12098159-B2 Solid forms of substituted benzoxaborole and compositions thereof BRIX1, CYP2F1, XDH PDE4B 3568/4885PDE4A 4313/4885PDE4C 4347/4885
US-20160235070-A1 FUNGICIDAL COMPOUNDS AND COMPOSITIONS OXA1L, BROX, CUL3 PDE4B 1090/4885PDE4A 1855/4885PDE4C 1436/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.