Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.68 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.68 |
| ▸ | TP53 | P04637 | 3/20 | 0.61 |
| ▸ | MDM4 | O15151 | 2/20 | 0.61 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.60 |
| ▸ | HPGD | P15428 | 2/20 | 0.56 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.56 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.56 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.56 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.56 |
| ▸ | POLB | P06746 | 1/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.55 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.55 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.55 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.55 |
| ▸ | GLA | P06280 | 1/20 | 0.55 |
| ▸ | NPC1 | O15118 | 2/20 | 0.53 |
| ▸ | RAB9A | P51151 | 2/20 | 0.53 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6445769 | 0.88 | TDP1 (0.58) | MAPTTDP1TP53MDM4MDM2 | |
| SCHEMBL1023209 | 0.85 | MAPT (0.83) | MAPTTDP1TP53MDM4MDM2 | |
| SCHEMBL34933 | 0.85 | TDP1 (0.72) | MAPTTDP1TP53MDM4MDM2 | |
| SCHEMBL28189189 | 0.84 | KMT2A (0.76) | MAPTTDP1TP53MDM4MDM2 | |
| SCHEMBL28896841 | 0.81 | TDP1 (1.00) | MAPTTDP1TP53MDM4MDM2 | |
| SCHEMBL1110180 | 0.80 | MDM4 (0.73) | MAPTTDP1TP53MDM4HPGD | |
| SCHEMBL28277559 | 0.78 | MAPT (0.62) | MAPTTDP1TP53MDM4MDM2 | |
| SCHEMBL1534076 | 0.78 | ALDH1A1 (0.55) | TP53MDM4MDM2HPGDMAPK1 | |
| SCHEMBL1490917 | 0.77 | MDM4 (0.63) | MAPTTDP1TP53MDM4MDM2 | |
| SCHEMBL6445765 | 0.76 | TDP1 (0.59) | MAPTTDP1TP53MDM4MDM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20020065151-A1 | Multi-piece solid golf ball | SUMITOMO RUBBER INDUSTRIES, LTD. (JP) | 2002-05-30 | — | — | US | disclosed |