Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.59 |
| ▸ | MAPT | P10636 | 2/20 | 0.59 |
| ▸ | TP53 | P04637 | 3/20 | 0.57 |
| ▸ | MDM4 | O15151 | 2/20 | 0.57 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.57 |
| ▸ | NPC1 | O15118 | 2/20 | 0.54 |
| ▸ | RAB9A | P51151 | 2/20 | 0.54 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.54 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.54 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.54 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.54 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.54 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.53 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.53 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.53 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.53 |
| ▸ | POLB | P06746 | 1/20 | 0.53 |
| ▸ | HPGD | P15428 | 1/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.53 |
| ▸ | LMNA | P02545 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL78295 | 0.94 | TDP1 (0.61) | TDP1MAPTTP53MDM4MDM2 | |
| SCHEMBL6445769 | 0.89 | TDP1 (0.58) | TDP1MAPTTP53MDM4MDM2 | |
| SCHEMBL34933 | 0.86 | TDP1 (0.72) | TDP1MAPTTP53MDM4MDM2 | |
| SCHEMBL4233761 | 0.86 | TDP1 (0.77) | TDP1MAPTTP53MDM4MDM2 | |
| SCHEMBL1023209 | 0.79 | MAPT (0.83) | TDP1MAPTTP53MDM4MDM2 | |
| SCHEMBL3785470 | 0.78 | LMNA (0.66) | MAPTTP53MDM4NPC1RAB9A | |
| SCHEMBL10614008 | 0.78 | KMT2A (0.68) | TDP1MAPTTP53MDM4NPC1 | |
| SCHEMBL1110180 | 0.78 | MDM4 (0.73) | TDP1MAPTTP53MDM4NPC1 | |
| SCHEMBL28189189 | 0.77 | KMT2A (0.76) | TDP1MAPTTP53MDM4MDM2 | |
| SCHEMBL6073016 | 0.77 | ALDH1A1 (0.56) | MAPTTP53MDM4MDM2NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0972792-B1 | A process for improving the properties of ground recycled rubber | GOODYEAR TIRE & RUBBER (US) | 2005-03-23 | — | — | EP | disclosed |
| US-6797757-B2 | RUBBER BLEND CONTAINING (TRI OR TETRA)SULFURDIPROPIONIC ACID | THE GOODYEAR TIRE & RUBBER COMPANY | 2004-09-28 | — | — | US | disclosed |
| EP-0937742-B1 | A process for improving the properties of ground recyled rubber | GOODYEAR TIRE & RUBBER (US) | 2004-08-11 | — | — | EP | disclosed |
| US-6660791-B2 | For recycling/wastes via grinding, compounding with carbon black, then vulcanizing with sulfur | THE GOODYEAR TIRE & RUBBER COMPANY | 2003-12-09 | — | — | US | disclosed |
| US-20030032685-A1 | Article, including tires, having component of rubber composition which contains particles of pre-vulcanized rubber and high purity trithiodipropionic acid | GOODYEAR TIRE & RUBBER COMPANY, THE | 2003-02-13 | — | — | US | disclosed |
| EP-1277793-A2 | Article having a component of a rubbber composition which contains particles of prevulcanized rubber and a blend of tetrathiodipropionic and trithiodipropionic acids | THE GOODYEAR TIRE & RUBBER COMPANY (US) | 2003-01-22 | — | — | EP | disclosed |
| US-20030004243-A1 | Article, including tires, having component of rubber composition which contains particles of pre-vulcanized rubber and blend of tetrathiodipropionic and trithiodipropionic acids | GOODYEAR TIRE & RUBBER COMPANY, THE | 2003-01-02 | — | — | US | disclosed |
| EP-1270661-A2 | Article having a component of a rubber composition which contains particles of pre-vulcanized rubber and high purity trithiodiproponic acid | THE GOODYEAR TIRE & RUBBER COMPANY (US) | 2003-01-02 | — | — | EP | disclosed |
| US-6407180-B1 | HOMOGENEOUS MIXING; HEATING | THE GOODYEAR TIRE & RUBBER COMPANY | 2002-06-18 | — | — | US | disclosed |
| US-6077874-A | DISPERSING TRIS/2-AMINOETHYL/AMINE IN ACETONE, DISPERSING INTO RECYCLED RUBBER HAVING SPECIFIED PARTICLE SIZE, MIXING WITH UNVULCANIZED RUBBER, HEATING TO VULCANIZE | THE GOODYEAR TIRE & RUBBER COMPANY (US) | 2000-06-20 | — | — | US | disclosed |
| EP-0972792-A1 | A process for improving the properties of ground recycled rubber | THE GOODYEAR TIRE & RUBBER COMPANY (US) | 2000-01-19 | — | — | EP | disclosed |
| EP-0937742-A1 | A process for improving the properties of ground recyled rubber | THE GOODYEAR TIRE & RUBBER COMPANY (US) | 1999-08-25 | — | — | EP | disclosed |
| US-5883139-A | HOMOGENEOUSLY DISPERSING WITH 3,3'TETRATHIODIPROPRIONIC ACID; MIXING WITH UNVULCANIZED RUBBER; HEATING, VULCANIZATION | THE GOODYEAR TIRE & RUBBER COMPANY (US) | 1999-03-16 | — | — | US | disclosed |
| US-5711904-A | Continuous mixing of silica loaded elastomeric compounds | THE GOODYEAR TIRE & RUBBER COMPANY (US) | 1998-01-27 | — | — | US | disclosed |
| WO-1997009162-A1 | CONTINUOUS MIXING OF SILICA LOADED ELASTOMERIC COMPOUNDS | THE GOODYEAR TIRE & RUBBER COMPANY (US) | 1997-03-13 | — | — | WO | disclosed |