Known targets — ChEMBL curated mechanism
AGTR1DHFRGABBR1GABBR2GABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGARTNR3C2PBP2XPTGS1PTGS2VKORC1blablaT-3blaT-4blaT-5blaT-6dacAdacBdacCfolAftsImrcAmrcBmrdApbp1apbp1bpbp2apbp2bpbp3polthyA
The experimentally established mechanism targets of Potassium Ion. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 1/20 | 0.30 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.30 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Potassium Ion SCHEMBL6063598 | 1.00 | CYP3A4 (0.30) | CYP3A4TSHRNFKB1NPSR1 | |
| SCHEMBL9345636 | 0.98 | CYP3A4 (0.32) | CYP3A4TSHRNFKB1NPSR1 | |
| Potassium Ion SCHEMBL11801342 | 0.85 | CYP3A4 (0.41) | CYP3A4TSHRNFKB1NPSR1 | |
| SCHEMBL305051 | 0.82 | APEX1 (0.30) | — | |
| SCHEMBL2277084 | 0.82 | APEX1 (0.30) | — | |
| SCHEMBL553869 | 0.81 | KDM4E (0.30) | — | |
| SCHEMBL27566062 | 0.81 | — | — | |
| Potassium Ion SCHEMBL6063243 | 0.73 | CA1 (0.32) | CYP3A4TSHRNFKB1NPSR1 | |
| Potassium Ion SCHEMBL6063235 | 0.73 | CA1 (0.32) | CYP3A4TSHRNFKB1NPSR1 | |
| SCHEMBL1259078 | 0.72 | CA4 (0.35) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 85 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9034357-B2 | Anti-adhesion barrier | COVIDIEN LP (US) | 2015-05-19 | — | — | US | claimed |
| EP-1778144-B1 | ANTI-ADHESION BARRIER | TYCO HEALTHCARE (US) | 2011-01-19 | — | — | EP | claimed |
| EP-1778144-A4 | ANTI-ADHESION BARRIER | TYCO HEALTHCARE (US) | 2009-08-19 | — | — | EP | claimed |
| US-20080140115-A1 | Stapling Support Structures | COVIDIEN LP | 2008-06-12 | — | — | US | claimed |
| JP-2008510515-A | — | — | 2008-04-10 | — | — | JP | claimed |
| US-20070280990-A1 | Anti-Adhesion Barrier | COVIDIEN LP | 2007-12-06 | — | — | US | claimed |
| EP-1791473-A2 | STAPLING SUPPORT STRUCTURES | TYCO HEALTHCARE GROUP LP (US) | 2007-06-06 | — | — | EP | claimed |
| EP-1778144-A2 | ANTI-ADHESION BARRIER | TYCO HEALTHCARE GROUP LP (US) | 2007-05-02 | — | — | EP | claimed |
| WO-2006023444-A2 | ANTI-ADHESION BARRIER | TYCO HEALTHCARE GROUP, LP (US) | 2006-03-02 | — | — | WO | claimed |
| WO-2006023578-A2 | STAPLING SUPPORT STRUCTURES | TYCO HEALTHCARE GROUP, LP (US) | 2006-03-02 | — | — | WO | claimed |
| EP-3569623-B1 | VINYL-LACTAM-BASED HYDROGEL COATINGS | CONSEJO SUPERIOR INVESTIGACION (ES) | 2023-08-09 | — | — | EP | disclosed |
| US-11634666-B2 | Methods for spore removal comprising a polysorbate surfactant and cationic antimicrobial mixture | 3M INNOVATIVE PROPERTIES COMPANY (US) | 2023-04-25 | — | — | US | disclosed |
| US-11572429-B2 | Hydrogels based on vinyl-caprolactam | CONSEJO SUPERIOR DE INVESTIGACIONES CIENTÍFICAS (CSIC) | 2023-02-07 | — | — | US | disclosed |
| EP-2744909-B1 | METHOD FOR PREPARING A BARRIER LAYER FOR A GLUCOSE SENSOR | BAXTER INT (US) | 2021-09-22 | — | — | EP | disclosed |
| CN-109971451-B | Graphene oxide nano cross-linking agent for fracturing fluid and preparation method thereof | 西南石油大学 | 2021-07-20 | — | — | CN | disclosed |
| US-5510399-A | Aqueous, high-solids synthetic rubber emulsion and its preparation | HUELS AKTIENGESELLSCHAFT (DE) | 1996-04-23 | — | — | US | disclosed |
| US-5417890-A | Polymer particles wrapped in shells of insoluble acrylamide polymers | THOMSON-CSF (FR) | 1995-05-23 | — | — | US | disclosed |
| EP-0335410-B1 | Water swellable resin composition | DAINICHISEIKA COLOR CHEM (JP) | 1994-09-28 | — | — | EP | disclosed |
| US-5026780-A | Sealing, waterproofing | DAINICHISEIKA COLOR & CHEMICALS MFG. CO., LTD. (JP) | 1991-06-25 | — | — | US | disclosed |
| EP-0335410-A2 | Water swellable resin composition | DAINICHISEIKA COLOR & CHEMICALS MFG. CO. LTD. (JP) | 1989-10-04 | — | — | EP | disclosed |