Known targets — ChEMBL curated mechanism
AGTR1DHFRGABBR1GABBR2GABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGARTNR3C2PBP2XPTGS1PTGS2VKORC1blablaT-3blaT-4blaT-5blaT-6dacAdacBdacCfolAftsImrcAmrcBmrdApbp1apbp1bpbp2apbp2bpbp3polthyA
The experimentally established mechanism targets of Potassium Ion. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 1/20 | 0.32 |
| ▸ | CA9 | Q16790 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 2/20 | 0.32 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.32 |
| ▸ | APEX1 | P27695 | 1/20 | 0.32 |
| ▸ | BBOX1 | O75936 | 1/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.30 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.30 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Potassium Ion SCHEMBL6063235 | 1.00 | CA1 (0.32) | CA1CA9TSHRALOX15APEX1 | |
| SCHEMBL2272261 | 0.80 | GABRP (0.40) | TSHR | |
| SCHEMBL1132712 | 0.80 | GABRP (0.40) | TSHR | |
| Potassium Ion SCHEMBL1023573 | 0.73 | CYP3A4 (0.30) | TSHRCYP3A4NFKB1NPSR1 | |
| Potassium Ion SCHEMBL6063598 | 0.73 | CYP3A4 (0.30) | TSHRCYP3A4NFKB1NPSR1 | |
| SCHEMBL27506502 | 0.73 | — | — | |
| SCHEMBL9345636 | 0.72 | CYP3A4 (0.32) | TSHRCYP3A4NFKB1NPSR1 | |
| SCHEMBL11831547 | 0.69 | BBOX1 (0.34) | TSHRALOX15APEX1BBOX1 | |
| SCHEMBL8973864 | 0.68 | — | — | |
| SCHEMBL16445575 | 0.68 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11634666-B2 | Methods for spore removal comprising a polysorbate surfactant and cationic antimicrobial mixture | 3M INNOVATIVE PROPERTIES COMPANY (US) | 2023-04-25 | — | — | US | disclosed |
| US-20180369118-A1 | METHODS FOR SPORE REMOVAL | 3M INNOVATIVE PROPERTIES COMPANY (US) | 2018-12-27 | — | — | US | disclosed |
| US-20180362895-A1 | METHODS FOR SPORE REMOVAL | 3M INNOVATIVE PROPERTIES COMPANY (US) | 2018-12-20 | — | — | US | disclosed |
| WO-2017112565-A1 | METHODS FOR SPORE REMOVAL | 3M INNOVATIVE PROPERTIES COMPANY (US) | 2017-06-29 | — | — | WO | disclosed |
| WO-2017112567-A1 | METHODS FOR SPORE REMOVAL | 3M INNOVATIVE PROPERTIES COMPANY (US) | 2017-06-29 | — | — | WO | disclosed |
| US-7012048-B2 | Composition and method for treating hair containing a cationic ampholytic polymer and an anionic benefit agent | NATIONAL STARCH AND CHEMICAL INVESTMENT HOLDING CORPORATION (US) | 2006-03-14 | — | — | US | disclosed |
| US-20040224862-A1 | Composition and method for treating hair containing a cationic ampholytic polymer and an anionic benefit agent | AKZO NOBEL N.V. (NL) | 2004-11-11 | — | — | US | disclosed |
| EP-1447075-A2 | Composition and method for treating hair containing a cationic ampholytic polymer and an anionic benefit agent | National Starch and Chemical Investment Holding Corporation (US) | 2004-08-18 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040224862-A1 | Composition and method for treating hair containing a cationic ampholytic polymer and an anionic benefit agent | KRT18, PSAP, AREG | CA1 79/4885CA9 98/4885TSHR 4532/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.