Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX1 | P07099 | 2/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | NAAA | Q02083 | 2/20 | 0.39 |
| ▸ | CYP19A1 | P11511 | 4/20 | 0.36 |
| ▸ | CA12 | O43570 | 2/20 | 0.35 |
| ▸ | CA1 | P00915 | 2/20 | 0.35 |
| ▸ | CA2 | P00918 | 2/20 | 0.35 |
| ▸ | CA9 | Q16790 | 2/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | MMP9 | P14780 | 2/20 | 0.32 |
| ▸ | MMP12 | P39900 | 2/20 | 0.32 |
| ▸ | MMP1 | P03956 | 1/20 | 0.32 |
| ▸ | FABP7 | O15540 | 1/20 | 0.31 |
| ▸ | FABP5 | Q01469 | 1/20 | 0.31 |
| ▸ | MMP2 | P08253 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1996146 | 0.84 | EPHX1 (0.48) | EPHX1HTTCYP2C19NAAACYP19A1 | |
| SCHEMBL4248940 | 0.82 | EPHX1 (0.43) | EPHX1HTTCYP2C19NAAACYP19A1 | |
| SCHEMBL5398616 | 0.82 | EPHX1 (0.43) | EPHX1HTTCYP2C19NAAACYP19A1 | |
| SCHEMBL4690944 | 0.82 | EPHX1 (0.46) | EPHX1HTTCYP2C19NAAACYP19A1 | |
| SCHEMBL11589171 | 0.81 | NAAA (0.50) | EPHX1HTTCYP2C19NAAACYP19A1 | |
| SCHEMBL2956734 | 0.81 | EPHX1 (0.42) | EPHX1HTTCYP2C19NAAACYP19A1 | |
| SCHEMBL8631017 | 0.81 | NAAA (0.50) | EPHX1HTTCYP2C19NAAACYP19A1 | |
| SCHEMBL8579936 | 0.81 | EPHX1 (0.42) | EPHX1HTTCYP2C19NAAACYP19A1 | |
| SCHEMBL1021168 | 0.81 | EPHX1 (0.42) | EPHX1HTTCYP2C19NAAACYP19A1 | |
| SCHEMBL1559459 | 0.81 | EPHX1 (0.42) | EPHX1HTTCYP2C19NAAACYP19A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 41 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117777110-A | Preparation method of candesartan cilexetil | 山西皇城相府药业股份有限公司 | 2024-03-29 | — | — | CN | claimed |
| CN-111747902-B | Candesartan cilexetil intermediate and application thereof | 浙江天宇药业股份有限公司 | 2022-08-09 | — | — | CN | claimed |
| CN-212523060-U | Distillation recovery device used in preparation of chloroethyl cyclohexyl carbonate | 金溪斯普瑞药业有限公司 | 2021-02-12 | — | — | CN | claimed |
| CN-111773754-A | Distillation recovery device used in preparation of chloroethyl cyclohexyl carbonate | 金溪斯普瑞药业有限公司 | 2020-10-16 | — | — | CN | claimed |
| CN-111747902-A | Candesartan cilexetil intermediate and application thereof | 浙江天宇药业股份有限公司 | 2020-10-09 | — | — | CN | claimed |
| CN-105153124-A | Preparation method of candesartan cilexetil | SHANXI HCXF PHARMACEUTICAL CO LTD | 2015-12-16 | — | — | CN | claimed |
| US-20090247595-A1 | Process for the preparation of tetrazolyl compounds | MEDICHEM, S.A. (ES) | 2009-10-01 | — | — | US | claimed |
| EP-1896455-A2 | PROCESS FOR THE PREPARATION OF TETRAZOLYL COMPOUNDS | Medichem, S.A. (ES) | 2008-03-12 | — | — | EP | claimed |
| WO-2007074399-A2 | PROCESS FOR THE PREPARATION OF TETRAZOLYL COMPOUNDS | MEDICHEM, S.A. (US) | 2007-07-05 | — | — | WO | claimed |
| CN-1666989-A | Candesartan Cilexetil preparing process | SHANXI AID PHARMACEUTICAL CO L (CN) | 2005-09-14 | — | — | CN | claimed |
| CN-117777110-A | Preparation method of candesartan cilexetil | 山西皇城相府药业股份有限公司 | 2024-03-29 | — | — | CN | disclosed |
| CN-117777110-A | Preparation method of candesartan cilexetil | 山西皇城相府药业股份有限公司 | 2024-03-29 | — | — | CN | disclosed |
| CN-117069704-A | Candesartan cilexetil and preparation method thereof | 安徽美诺华药物化学有限公司 | 2023-11-17 | — | — | CN | disclosed |
| CN-111747902-B | Candesartan cilexetil intermediate and application thereof | 浙江天宇药业股份有限公司 | 2022-08-09 | — | — | CN | disclosed |
| CN-113912588-A | Synthetic process method of candesartan cilexetil | 绍兴市上虞区武汉理工大学高等研究院 | 2022-01-11 | — | — | CN | disclosed |
| WO-2007074399-A2 | PROCESS FOR THE PREPARATION OF TETRAZOLYL COMPOUNDS | MEDICHEM, S.A. (US) | 2007-07-05 | — | — | WO | disclosed |
| CN-1666989-A | Candesartan Cilexetil preparing process | SHANXI AID PHARMACEUTICAL CO L (CN) | 2005-09-14 | — | — | CN | disclosed |
| CN-1666989-A | Candesartan Cilexetil preparing process | SHANXI AID PHARMACEUTICAL CO L (CN) | 2005-09-14 | — | — | CN | disclosed |
| EP-0846119-A1 | THIENOPYRIMIDINE DERIVATIVES, THEIR PRODUCTION AND USE | Takeda Chemical Industries, Ltd. (JP) | 1998-06-10 | — | — | EP | disclosed |
| WO-1997007119-A1 | THIENOPYRIMIDINE DERIVATIVES, THEIR PRODUCTION AND USE | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1997-02-27 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090247595-A1 | Process for the preparation of tetrazolyl compounds | TLL1, TLL2, TPP1 | EPHX1 2595/4885HTT 3214/4885CYP2C19 3090/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.