SCHEMBL10239126

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL13556205	0.90	ALDH1A1 (0.33)	ALDH1A1MEN1KMT2AL3MBTL1CA12
	SCHEMBL12094555	0.86	ALDH1A1 (0.42)	ALDH1A1MEN1KMT2AL3MBTL1CA12
	SCHEMBL10098842	0.85	ALDH1A1 (0.40)	ALDH1A1MEN1KMT2AL3MBTL1CA12
	SCHEMBL13706078	0.85	LMNA (0.46)	ALDH1A1MEN1KMT2ACA12CA2
	SCHEMBL16605508	0.85	ALDH1A1 (0.43)	ALDH1A1MEN1KMT2AL3MBTL1CA12
	SCHEMBL13556217	0.82	HSD11B1 (0.37)	ALDH1A1EPHX2
	SCHEMBL10239122	0.81	ALDH1A1 (0.38)	ALDH1A1MEN1KMT2AL3MBTL1CA12
	SCHEMBL13556208	0.81	ALDH1A1 (0.32)	ALDH1A1MEN1KMT2AL3MBTL1
	SCHEMBL16140247	0.80	ALDH1A1 (0.40)	ALDH1A1MEN1KMT2AL3MBTL1CA12
	SCHEMBL14818361	0.80	GBA2 (0.37)	ALDH1A1MEN1KMT2AL3MBTL1CA12

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.