Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPA1 | O75762 | 4/20 | 0.33 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.33 |
| ▸ | GPR3 | P46089 | 1/20 | 0.32 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.31 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.31 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.31 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.31 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.31 |
| ▸ | MPI | P34949 | 1/20 | 0.31 |
| ▸ | CTSC | P53634 | 1/20 | 0.30 |
| ▸ | KCNQ3 | O43525 | 1/20 | 0.30 |
| ▸ | KCNQ2 | O43526 | 1/20 | 0.30 |
| ▸ | KCNQ1 | P51787 | 1/20 | 0.30 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.30 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.30 |
| ▸ | CA12 | O43570 | 1/20 | 0.30 |
| ▸ | CA9 | Q16790 | 1/20 | 0.30 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1026104 | 0.78 | TRPA1 (0.37) | TRPA1GPR3KCNQ3KCNQ2KCNQ1 | |
| SCHEMBL895932 | 0.74 | — | — | |
| SCHEMBL1034447 | 0.73 | HRH4 (0.30) | — | |
| SCHEMBL261330 | 0.73 | GPR3 (0.36) | GPR3NOTUMHDAC3HDAC1HDAC2 | |
| SCHEMBL2305437 | 0.71 | SLC7A5 (0.40) | TRPA1SLC7A5HDAC3HDAC1HDAC2 | |
| SCHEMBL2777134 | 0.70 | GPR3 (0.33) | GPR3NOTUMSCN5ASCN9A | |
| SCHEMBL394514 | 0.69 | ALDH1A1 (0.38) | — | |
| SCHEMBL2178735 | 0.69 | NQO1 (0.38) | — | |
| SCHEMBL25353609 | 0.69 | SLC7A5 (0.41) | TRPA1SLC7A5GPR3NOTUMHDAC3 | |
| SCHEMBL27799385 | 0.68 | CTSC (0.37) | TRPA1SLC7A5GPR3HDAC3HDAC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 79 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6638956-B2 | Pesticidal 1-arylpyrazoles | RHONE-POULENC, INC. | 2003-10-28 | — | — | US | claimed |
| US-20030144251-A1 | Pesticidal 1-arylpyrazoles | RHONE-POULENC INC. | 2003-07-31 | — | — | US | claimed |
| US-6593328-B2 | Said compounds for the control of arthropod, nematode, helminth or protozoan pests, in particular to the application of said compounds or compositions in agricultural methods of use, particularly as pesticides, for controlling arthropods, | RHONE-POULENC INC. | 2003-07-15 | — | — | US | claimed |
| US-20030092680-A1 | Novel pesticides | WU TAI-TEH (US) | 2003-05-15 | — | — | US | claimed |
| US-6500848-B2 | INSECTICIDE, NEMATODICES, ANTIPROTOZOA AGENTS; VETERINARY MEDICINE | RHONE-POULENC INC. | 2002-12-31 | — | — | US | claimed |
| US-20020173492-A1 | Novel pesticides | WU TAI-TEH (US) | 2002-11-21 | — | — | US | claimed |
| US-6376520-B1 | INSECTICIDES, NEMATOCIDES | RHONE-POULENC, INC. | 2002-04-23 | — | — | US | claimed |
| US-20020045758-A1 | Pesticidal 1-arylpyrazoles | RHONE-POULENC INC. | 2002-04-18 | — | — | US | claimed |
| US-6346522-B1 | 1-ARYLPYRAZOLES; SYSTEMIC PESTICIDES, INSECTICIDES, LARVICIDES, MITICIDES, ANTIPROTOZOA, AND ANTHELMINTIC AGENTS; AGRICULTURE, HORTICULTURE, ANIMAL HUSBANDRY, PUBLIC HEALTH AND VETERINARY MEDICINE | RHONE-POULENC, INC. | 2002-02-12 | — | — | US | claimed |
| US-20020016468-A1 | PESTICIDAL 1-ARYLPYRAZOLE DERIVATIVES | RHONE-POULENC AGROCHIMIE (FR) | 2002-02-07 | — | — | US | claimed |
| EP-0948487-A1 | PESTICIDAL 1-ARYL AND PYRIDYLPYRAZOLE DERIVATIVES | RHONE-POULENC AGROCHIMIE (FR) | 1999-10-13 | — | — | EP | claimed |
| US-5914335-A | INSECTICIDES | RHONE-POULENC INC. (US) | 1999-06-22 | — | — | US | claimed |
| EP-0911329-A1 | 3-Substituted arylpyrazole derivatives | RHONE-POULENC AGRO (FR) | 1999-04-28 | — | — | EP | claimed |
| WO-1998028279-A1 | PESTICIDAL 1-ARYL AND PYRIDYLPYRAZOLE DERIVATIVES | RHONE-POULENC AGROCHIMIE (FR) | 1998-07-02 | — | — | WO | claimed |
| CN-1184810-A | Pesticidal 1 -arylpyrazole -5 -sulfinilimine derivatives | RHONE POULENC AGROCHIMIE (FR) | 1998-06-17 | — | — | CN | claimed |
| EP-0839809-A1 | Pesticidal 1-arylpyrazole-5-sulfinilimine derivatives | RHONE-POULENC AGROCHIMIE (FR) | 1998-05-06 | — | — | EP | claimed |
| US-5691333-A | APPLYING TO CONTROL ARTHROPODS AND NEMATODES | RHONE-POULENC INC. (US) | 1997-11-25 | — | — | US | claimed |
| US-5629335-A | Pesticidal 1-arylpyrazole-3-carboximidothioic acid esters | RHONE-POULENC INC. (US) | 1997-05-13 | — | — | US | claimed |
| US-5556873-A | AGRICULTURAL PESTICIDES | RHONE-POULENC INC. (US) | 1996-09-17 | — | — | US | claimed |
| US-5236938-A | Pesticidal 1-aryl-5-(substituted alkylideneimino)pyrazoles | RHONE-POULENC INC. (US) | 1993-08-17 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020173492-A1 | Novel pesticides | DDT, ACHE, PTMS | TRPA1 76/4885SLC7A5 2300/4885GPR3 1789/4885 |
| US-20020045758-A1 | Pesticidal 1-arylpyrazoles | CYP1B1, CYP2E1, CYP1A1 | TRPA1 252/4885SLC7A5 4354/4885GPR3 1191/4885 |
| US-20030144251-A1 | Pesticidal 1-arylpyrazoles | CYP1B1, CYP2E1, CYP1A1 | TRPA1 252/4885SLC7A5 4354/4885GPR3 1191/4885 |
| US-20020016468-A1 | PESTICIDAL 1-ARYLPYRAZOLE DERIVATIVES | DDT, NAT1, CYP2E1 | TRPA1 147/4885SLC7A5 3278/4885GPR3 263/4885 |
| US-20030092680-A1 | Novel pesticides | DDT, ACHE, PTMS | TRPA1 76/4885SLC7A5 2300/4885GPR3 1789/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.