SCHEMBL10243682

SCHEMBL10243682

COC(=O)NCCN(C)C

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
EPHX1 P07099 1/20 0.48
DNM1 Q05193 1/20 0.46
CA1 P00915 2/20 0.45
CA2 P00918 2/20 0.45
CA12 O43570 1/20 0.45
CA9 Q16790 1/20 0.45
ALDH1A1 P00352 1/20 0.42
PRMT3 O60678 1/20 0.40
CARM1 Q86X55 1/20 0.40
PRMT6 Q96LA8 1/20 0.40
PRMT1 Q99873 1/20 0.40
PRMT8 Q9NR22 1/20 0.40
CYP1A2 P05177 1/20 0.40
HTT P42858 1/20 0.40
SMN1; SMN2 Q16637 1/20 0.40
MAPK1 P28482 1/20 0.40
LGALS1 P09382 1/20 0.39
CYP2D6 P10635 1/20 0.39
NPSR1 Q6W5P4 1/20 0.38
USP2 O75604 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22699558 0.85 DNM1 (0.42) EPHX1DNM1CA1CA2CA12
SCHEMBL31323004 0.80 EPHX1 (0.44) EPHX1DNM1ALDH1A1
SCHEMBL2335068 0.80 ALDH1A1 (0.46) DNM1CA1CA2CA12CA9
SCHEMBL3190326 0.79 EPHX1 (0.61) EPHX1ALDH1A1USP2
SCHEMBL1979026 0.79 TDP1 (0.55) EPHX1DNM1CA1CA2CA12
SCHEMBL20123376 0.79 DNM1 (0.41) DNM1CA1CA2CA12CA9
SCHEMBL22605262 0.79 DNM1 (0.41) DNM1CA1CA2CA12CA9
SCHEMBL13525915 0.79 ALDH1A1 (0.41) DNM1CA1CA2CA12CA9
SCHEMBL13037027 0.77 EPHX1 (0.50) EPHX1ALDH1A1CYP1A2SMN1; SMN2MAPK1
SCHEMBL20149660 0.77 PRMT3 (0.37) EPHX1DNM1CA1CA2CA12

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 36 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4734954-A1 LIPID NANOPARTICLE FORMULATIONS FOR CELL THERAPY AND RELATED METHODS Global Life Sciences Solutions Canada ULC (CA) 2026-05-06 EP disclosed
WO-2025005991-A1 LIPID NANOPARTICLE FORMULATIONS FOR CELL THERAPY AND RELATED METHODS GLOBAL LIFE SCIENCES SOLUTIONS CANADA ULC (CA) 2025-01-02 WO disclosed
EP-4272825-A2 MTORC MODULATORS AND USES THEREOF Aeovian Pharmaceuticals, Inc. (US) 2023-11-08 EP disclosed
US-20230331737-A1 MTORC1 MODULATORS AND USES THEREOF AEOVIAN PHARMACEUTICALS, INC. 2023-10-19 US disclosed
WO-2023178299-A1 PRODRUGS OF GANAXOLONE MARINUS PHARMACEUTICALS, INC. (US) 2023-09-21 WO disclosed
US-11230557-B2 mTORC modulators and uses thereof AEOVIAN PHARMACEUTICALS, INC. (US) 2022-01-25 US disclosed
US-11021492-B2 mTORC modulators and uses thereof AEOVIAN PHARMACEUTICALS, INC. (US) 2021-06-01 US disclosed
US-20210008041-A1 MTORC MODULATORS AND USES THEREOF AEOVIAN PHARMACEUTICALS, INC. 2021-01-14 US disclosed
US-20210002300-A1 MTORC MODULATORS AND USES THEREOF AEOVIAN PHARMACEUTICALS, INC. 2021-01-07 US disclosed
US-20200239439-A1 HETEROARYL COMPOUNDS AS CXCR4 INHIBITORS, COMPOSITION AND METHOD USING THE SAME Suzhou Yunxuan Yiyao Keji Youxian Gongsi (CN) 2020-07-30 US disclosed
US-8071764-B2 Compounds of reverse turn mimetics and the use thereof (2) CHOONGWAE PHARMA CORPORATION (KR) 2011-12-06 US disclosed
US-20110077404-A1 PROCESS FOR PREPARING ENANTIOMERICALLY PURE INDOLOPYRIDINES 4SC AG (DE) 2011-03-31 US disclosed
US-20110077404-A1 PROCESS FOR PREPARING ENANTIOMERICALLY PURE INDOLOPYRIDINES 4SC AG (DE) 2011-03-31 US disclosed
US-20100286094-A1 NOVEL COMPOUNDS OF REVERSE TURN MIMETICS AND THE USE THEREOF CHOONGWAE PHARMA CORPORATION (KR) 2010-11-11 US disclosed
US-20100228027-A1 NOVEL COMPOUNDS OF REVERSE TURN MIMETICS AND THE USE THEREOF (2) CHOONGWAE PHARMA CORPORATION (KR) 2010-09-09 US disclosed
EP-1513814-B1 NOVEL PIPERIDINE COMPOUND MITSUBISHI TANABE PHARMA CORP (JP) 2010-03-17 EP disclosed
US-7619092-B2 Piperidine compounds MITSUBISHI TANABE PHARMA CORPORATION (JP) 2009-11-17 US disclosed
US-7619092-B2 Piperidine compounds MITSUBISHI TANABE PHARMA CORPORATION (JP) 2009-11-17 US disclosed
US-20090281292-A1 10a-Azalide Compound MEIJI SEIKA PHARMA CO., LTD. (JP) 2009-11-12 US disclosed
US-20090281292-A1 10a-Azalide Compound MEIJI SEIKA PHARMA CO., LTD. (JP) 2009-11-12 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (10 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100286094-A1 NOVEL COMPOUNDS OF REVERSE TURN MIMETICS AND THE USE THEREOF MCL1, MYADM, FLT3 EPHX1 3270/4885DNM1 3548/4885CA1 1138/4885
US-20110077404-A1 PROCESS FOR PREPARING ENANTIOMERICALLY PURE INDOLOPYRIDINES GRIK5, CYP3A5, GRK5 EPHX1 1297/4885DNM1 1334/4885CA1 2933/4885
US-20100228027-A1 NOVEL COMPOUNDS OF REVERSE TURN MIMETICS AND THE USE THEREOF (2) MCL1, BID, MYADM EPHX1 3009/4885DNM1 3039/4885CA1 1224/4885
US-20210008041-A1 MTORC MODULATORS AND USES THEREOF MTOR, RICTOR, RPTOR EPHX1 4841/4885DNM1 785/4885CA1 4866/4885
US-11230557-B2 mTORC modulators and uses thereof MTOR, RICTOR, RPTOR EPHX1 4841/4885DNM1 785/4885CA1 4866/4885
US-20230331737-A1 MTORC1 MODULATORS AND USES THEREOF MTOR, RPTOR, RICTOR EPHX1 4787/4885DNM1 339/4885CA1 4771/4885
US-20210002300-A1 MTORC MODULATORS AND USES THEREOF MTOR, RICTOR, RPTOR EPHX1 4841/4885DNM1 785/4885CA1 4866/4885
US-20200239439-A1 HETEROARYL COMPOUNDS AS CXCR4 INHIBITORS, COMPOSITION AND METHOD USING THE SAME CXCR4, CXCL12, CXCR1 EPHX1 1231/4885DNM1 1454/4885CA1 4725/4885
US-20090281292-A1 10a-Azalide Compound IL17A, AZI2, HDAC9 EPHX1 1924/4885DNM1 3156/4885CA1 3677/4885
US-11021492-B2 mTORC modulators and uses thereof MTOR, RICTOR, RPTOR EPHX1 4841/4885DNM1 785/4885CA1 4866/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.