Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DNM1 | Q05193 | 1/20 | 0.41 |
| ▸ | CA1 | P00915 | 2/20 | 0.39 |
| ▸ | CA2 | P00918 | 2/20 | 0.39 |
| ▸ | CA12 | O43570 | 1/20 | 0.39 |
| ▸ | CA9 | Q16790 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | ACHE | P22303 | 6/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | CHRNB2 | P17787 | 3/20 | 0.38 |
| ▸ | CHRNA4 | P43681 | 3/20 | 0.38 |
| ▸ | CHRNB4 | P30926 | 2/20 | 0.38 |
| ▸ | CHRNA3 | P32297 | 2/20 | 0.38 |
| ▸ | USP2 | O75604 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | ANPEP | P15144 | 1/20 | 0.37 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.36 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.36 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.36 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2335068 | 0.82 | ALDH1A1 (0.46) | DNM1CA1CA2CA12CA9 | |
| SCHEMBL22605262 | 0.80 | DNM1 (0.41) | DNM1CA1CA2CA12CA9 | |
| SCHEMBL10243682 | 0.79 | EPHX1 (0.48) | DNM1CA1CA2CA12CA9 | |
| SCHEMBL27626834 | 0.78 | ACHE (0.55) | DNM1ACHECHRNB2CHRNA4CHRNB4 | |
| SCHEMBL11375714 | 0.77 | MAPT (0.49) | DNM1CYP2C9CYP2C19ACHECHRNB2 | |
| SCHEMBL15148178 | 0.77 | SMN1; SMN2 (0.46) | DNM1CA1CA2CA12CA9 | |
| SCHEMBL20123338 | 0.76 | — | — | |
| SCHEMBL4654311 | 0.76 | ACHE (0.43) | DNM1ACHECHRNB2CHRNA4CHRNB4 | |
| SCHEMBL20123405 | 0.75 | PAOX (0.47) | ACHEALDH1A1 | |
| SCHEMBL21359262 | 0.73 | ACHE (0.70) | ACHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2620436-B1 | SUBSTITUTED POLYCYCLIC CARBAMOYL PYRIDONE DERIVATIVE PRODRUG | SHIONOGI & CO (JP) | 2018-05-09 | — | — | EP | disclosed |