SCHEMBL20149660

SCHEMBL20149660

COC(=O)NNCCN(C)C

nearest known ligand 0.37

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PRMT3 O60678 1/20 0.37
CARM1 Q86X55 1/20 0.37
PRMT6 Q96LA8 1/20 0.37
PRMT1 Q99873 1/20 0.37
PRMT8 Q9NR22 1/20 0.37
ANPEP P15144 1/20 0.35
DNM1 Q05193 1/20 0.35
ALDH1A1 P00352 3/20 0.34
MEN1 O00255 1/20 0.34
KMT2A Q03164 1/20 0.34
CHRM2 P08172 1/20 0.34
CHRM4 P08173 1/20 0.34
CHRM5 P08912 1/20 0.34
CHRM1 P11229 1/20 0.34
CHRNB2 P17787 1/20 0.34
CHRM3 P20309 1/20 0.34
CHRNA4 P43681 1/20 0.34
CA1 P00915 2/20 0.33
CA2 P00918 2/20 0.33
CA12 O43570 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10243682 0.77 EPHX1 (0.48) PRMT3CARM1PRMT6PRMT1PRMT8
SCHEMBL10860218 0.76 PRMT3 (0.39) PRMT3CARM1PRMT6PRMT1PRMT8
SCHEMBL2776894 0.75
SCHEMBL8698181 0.75
SCHEMBL7864541 0.71 PAOX (0.46) PRMT3CARM1PRMT6PRMT1PRMT8
SCHEMBL536155 0.69
SCHEMBL22699558 0.68 DNM1 (0.42) PRMT3CARM1PRMT6PRMT1PRMT8
SCHEMBL27614821 0.68 ALDH1A1 (0.40) ALDH1A1MEN1KMT2ACHRM2CHRM4
SCHEMBL10855415 0.67 PRMT3 (0.39) PRMT3CARM1PRMT6PRMT1PRMT8
SCHEMBL10855029 0.67 CA1 (0.43) PRMT3CARM1PRMT6PRMT1PRMT8

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2018087753-A1 CATIONIC LIPIDS FOR NUCLEIC ACID DELIVERY AND PREPARATION THEREOF TECHNOLOGY INNOVATION MOMENTUM FUND (ISRAEL) LIMITED PARTNERSHIP (IL) 2018-05-17 WO disclosed