SCHEMBL1024380

SCHEMBL1024380

O=C(O)c1ccc([N+](=O)[O-])cc1I

nearest known ligand 0.64

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 5/20 0.64
TDP1 Q9NUW8 3/20 0.64
CYP3A4 P08684 1/20 0.64
ALOX15 P16050 1/20 0.64
MAPT P10636 2/20 0.54
KMT2A Q03164 4/20 0.50
HTT P42858 2/20 0.50
TP53 P04637 2/20 0.50
MEN1 O00255 2/20 0.50
LMNA P02545 1/20 0.50
CTSV O60911 1/20 0.50
CTSL P07711 1/20 0.50
SMN1; SMN2 Q16637 2/20 0.49
MAOA P21397 1/20 0.49
MAOB P27338 1/20 0.49
CES2 O00748 1/20 0.47
AKR1C4 P17516 1/20 0.47
AKR1C3 P42330 1/20 0.47
AKR1C2 P52895 1/20 0.47
AKR1C1 Q04828 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3550116 0.85 ALDH1A1 (0.59) ALDH1A1TDP1CYP3A4ALOX15MAPT
SCHEMBL7422406 0.84 KMT2A (0.65) ALDH1A1TDP1CYP3A4ALOX15KMT2A
SCHEMBL19971993 0.84 ALDH1A1 (0.52) ALDH1A1TDP1CYP3A4ALOX15MAPT
SCHEMBL260006 0.82 ALDH1A1 (0.70) ALDH1A1TDP1CYP3A4ALOX15MAPT
SCHEMBL27278834 0.82 CES2 (0.56) ALDH1A1TDP1CYP3A4ALOX15MAPT
SCHEMBL11810168 0.81 ALDH1A1 (0.68) ALDH1A1TDP1CYP3A4ALOX15MAPT
Hydrochloric Acid SCHEMBL10694666 0.81 ALDH1A1 (0.68) ALDH1A1TDP1CYP3A4ALOX15MAPT
SCHEMBL7824186 0.81 ALDH1A1 (0.68) ALDH1A1TDP1CYP3A4ALOX15MAPT
Hydrochloric Acid SCHEMBL10694658 0.81 ALDH1A1 (0.68) ALDH1A1TDP1CYP3A4ALOX15MAPT
SCHEMBL11351093 0.81 ALDH1A1 (0.68) ALDH1A1TDP1CYP3A4ALOX15MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 167 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10546303-B2 Optically visible carbon nanotube with nanocrystals decoration as unique ID INTERNATIONAL BUSINESS MACHINES CORPORATION (US) 2020-01-28 US claimed
US-20180276682-A1 Optically Visible Carbon Nanotube with Nanocrystals Decoration as Unique ID INTERNATIONAL BUSINESS MACHINES CORPORATION 2018-09-27 US claimed
US-20150290344-A1 BIODEGRADABLE POLYESTER- AND POLY(ESTER AMIDE) BASED X-RAY IMAGING AGENTS CLEMSON UNIVERSITY RESEARCH FOUNDATION 2015-10-15 US claimed
CN-1112548-A Polyiodinated compounds, process for preparing them and diagnostic compositions GUERBET SA (FR) 1995-11-29 CN claimed
EP-3972649-B1 MCL-1 INHIBITOR ANTIBODY-DRUG CONJUGATES AND METHODS OF USE NOVARTIS AG (CH) 2026-05-13 EP disclosed
EP-4717316-A2 ANTI-EGFR ANTIBODY-DRUG CONJUGATES AbbVie Inc. (US) 2026-04-01 EP disclosed
US-20260027220-A1 EPHA2 BCL-XL INHIBITOR ANTIBODY-DRUG CONJUGATES AND METHODS OF USE THEREOF NOVARTIS AG (CH) 2026-01-29 US disclosed
EP-4663628-A1 NEW COMPOUND AND PHARMACEUTICAL COMPOSITION COMPRISING SAME Samjin Pharmaceutical Co., Ltd. (KR) 2025-12-17 EP disclosed
US-20250339547-A1 MET BCL-XL INHIBITOR ANTIBODY-DRUG CONJUGATES AND METHODS OF USE THEREOF NOVARTIS AG (CH) 2025-11-06 US disclosed
US-20250263491-A1 ANTI-EGFR ANTIBODY DRUG CONJUGATES ABBVIE INC (US) 2025-08-21 US disclosed
US-20250213685-A1 ANTI-EGFR ANTIBODY DRUG CONJUGATES ABBVIE INC (US) 2025-07-03 US disclosed
US-20250177374-A1 BCL-XL Inhibitory Compounds Having Low Cell Permeability and Antibody Drug Conjugates Including the Same ABBVIE INC (US) 2025-06-05 US disclosed
US-20040122038-A1 NPY-5 antagonists PFIZER INC 2004-06-24 US disclosed
CN-1112548-A Polyiodinated compounds, process for preparing them and diagnostic compositions GUERBET SA (FR) 1995-11-29 CN disclosed
EP-0468683-B1 Fungicidal acylamidobenzamides ZENECA LTD (GB) 1995-06-14 EP disclosed
CN-1058392-A Mycocide ICI PLC (GB) 1992-02-05 CN disclosed
EP-0468683-A1 Fungicidal acylamidobenzamides ZENECA LIMITED (GB) 1992-01-29 EP disclosed
EP-0098098-B1 ACRIDINECARBOXAMIDE COMPOUNDS DEVELOPMENT FINANCE CORPORATION OF NEW ZEALAND (NZ) 1989-02-08 EP disclosed
US-4590277-A BACTERICIDES, ANTITUMOR AGENTS DEVELOPMENT FINANCE CORPORATION OF NEW ZEALAND (NZ) 1986-05-20 US disclosed
EP-0098098-A2 Acridinecarboxamide compounds DEVELOPMENT FINANCE CORPORATION OF NEW ZEALAND (NZ) 1984-01-11 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20150290344-A1 BIODEGRADABLE POLYESTER- AND POLY(ESTER AMIDE) BASED X-RAY IMAGING AGENTS PUF60, ARG1, PAM ALDH1A1 3356/4885TDP1 1122/4885CYP3A4 2600/4885
US-20250213685-A1 ANTI-EGFR ANTIBODY DRUG CONJUGATES EGFR, ERBB2, ERBB3 ALDH1A1 1891/4885TDP1 4598/4885CYP3A4 3894/4885
US-20260027220-A1 EPHA2 BCL-XL INHIBITOR ANTIBODY-DRUG CONJUGATES AND METHODS OF USE THEREOF EPHA2, EPHA1, EPHB1 ALDH1A1 951/4885TDP1 3222/4885CYP3A4 3236/4885
US-20250339547-A1 MET BCL-XL INHIBITOR ANTIBODY-DRUG CONJUGATES AND METHODS OF USE THEREOF MET, BCL3, BCL9 ALDH1A1 2347/4885TDP1 4095/4885CYP3A4 3014/4885
US-20250263491-A1 ANTI-EGFR ANTIBODY DRUG CONJUGATES EGFR, ERBB2, ERBB3 ALDH1A1 1891/4885TDP1 4598/4885CYP3A4 3894/4885
US-20040122038-A1 NPY-5 antagonists NPY5R, NPY1R, NPY2R ALDH1A1 2832/4885TDP1 2467/4885CYP3A4 3008/4885
US-20250177374-A1 BCL-XL Inhibitory Compounds Having Low Cell Permeability and Antibody Drug Conjugates Including the Same BCL2, BAX, BCL9 ALDH1A1 2826/4885TDP1 3899/4885CYP3A4 4366/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.