Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LOXL2 | Q9Y4K0 | 3/20 | 0.49 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.46 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.46 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.46 |
| ▸ | FLT1 | P17948 | 1/20 | 0.46 |
| ▸ | FGFR3 | P22607 | 1/20 | 0.46 |
| ▸ | KDR | P35968 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.45 |
| ▸ | HPGD | P15428 | 3/20 | 0.44 |
| ▸ | GAA | P10253 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | SIRT6 | Q8N6T7 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | KAT2B | Q92831 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL5411433 | 0.99 | LOXL2 (0.47) | LOXL2PDGFRBFGFR1PDGFRAFLT1 | |
| SCHEMBL30434912 | 0.88 | SIRT6 (0.52) | LOXL2PDGFRBFGFR1PDGFRAFLT1 | |
| SCHEMBL148602 | 0.88 | SIRT6 (0.52) | LOXL2PDGFRBFGFR1PDGFRAFLT1 | |
| SCHEMBL13634220 | 0.88 | ALDH1A1 (0.48) | PDGFRBFGFR1PDGFRAFLT1FGFR3 | |
| Hydrochloric Acid SCHEMBL8650383 | 0.87 | SIRT6 (0.51) | LOXL2PDGFRBFGFR1PDGFRAFLT1 | |
| SCHEMBL590781 | 0.87 | TTR (0.47) | PDGFRBFGFR1PDGFRAFLT1FGFR3 | |
| SCHEMBL4627839 | 0.86 | PDGFRB (0.44) | PDGFRBFGFR1PDGFRAFLT1FGFR3 | |
| SCHEMBL2277745 | 0.85 | PDGFRB (0.46) | PDGFRBFGFR1PDGFRAFLT1FGFR3 | |
| SCHEMBL2771843 | 0.85 | PDGFRB (0.46) | PDGFRBFGFR1PDGFRAFLT1FGFR3 | |
| SCHEMBL2770959 | 0.85 | HPGD (0.46) | PDGFRBFGFR1PDGFRAFLT1FGFR3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103524386-B | The preparation method of 2-amino-4-Methanesulfomide methyl toluate | JIANGSU DINGLONG TECHNOLOGY CO., LTD. (CN) | 2016-05-18 | — | — | CN | disclosed |
| US-20150094474-A1 | AGRICULTURAL CHEMICALS | REDAG CROP PROTECTION LTD (GB) | 2015-04-02 | — | — | US | disclosed |
| US-20150094474-A1 | AGRICULTURAL CHEMICALS | REDAG CROP PROTECTION LTD (GB) | 2015-04-02 | — | — | US | disclosed |
| CN-103524386-A | Method for preparing 2-amino-4-methanesulfonamide methylbenzoate | BINHAI BAIYUN CHEMICAL CO LTD | 2014-01-22 | — | — | CN | disclosed |
| US-20130261130-A1 | NEUROTRYPSIN INHIBITORS | NEUROTUNE AG (CH) | 2013-10-03 | — | — | US | disclosed |
| US-20130261130-A1 | NEUROTRYPSIN INHIBITORS | NEUROTUNE AG (CH) | 2013-10-03 | — | — | US | disclosed |
| WO-2013136073-A1 | AGRICULTURAL CHEMICALS | REDX PHARMA LIMITED (GB) | 2013-09-19 | — | — | WO | disclosed |
| WO-2012059442-A2 | NEUROTRYPSIN INHIBITORS | NEUROTUNE AG (CH) | 2012-05-10 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150094474-A1 | AGRICULTURAL CHEMICALS | DDT, SQOR, GPX4 | LOXL2 1156/4885PDGFRB 4832/4885FGFR1 3487/4885 |
| US-20130261130-A1 | NEUROTRYPSIN INHIBITORS | MTPN, CHRNA7, CHRNA10 | LOXL2 4624/4885PDGFRB 2993/4885FGFR1 1455/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.