Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | ATM | Q13315 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27213267 | 0.83 | — | — | |
| SCHEMBL21325317 | 0.80 | RAB9A (0.32) | LMNAPOLBRAB9AATML3MBTL1 | |
| SCHEMBL1911594 | 0.80 | SLC6A3 (0.40) | LMNAPOLBRAB9AATML3MBTL1 | |
| SCHEMBL4548402 | 0.79 | PDK1 (0.33) | — | |
| SCHEMBL1912687 | 0.78 | L3MBTL1 (0.49) | LMNAPOLBRAB9AATML3MBTL1 | |
| SCHEMBL13010776 | 0.77 | LMNA (0.30) | LMNAPOLBRAB9AATML3MBTL1 | |
| SCHEMBL11922170 | 0.77 | SLC6A3 (0.45) | LMNAPOLBRAB9AATML3MBTL1 | |
| SCHEMBL3072164 | 0.75 | — | — | |
| SCHEMBL4548405 | 0.74 | SMN1; SMN2 (0.43) | LMNA | |
| SCHEMBL1911586 | 0.74 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9314025-B2 | Mixtures of mesoionic pesticides | E I DU PONT DE NEMOURS AND COMPANY (US) | 2016-04-19 | — | — | US | disclosed |
| US-9018220-B2 | Mesoionic pesticides | E I DU PONT DE NEMOURS AND COMPANY (US) | 2015-04-28 | — | — | US | disclosed |
| US-20140187776-A1 | MIXTURES OF MESOIONIC PESTICIDES | E I DU PONT DE NEMOURS AND COMPANY (US) | 2014-07-03 | — | — | US | disclosed |
| US-8552007-B2 | Mesoionic pesticides | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 2013-10-08 | — | — | US | disclosed |
| US-20120115722-A1 | MIXTURES OF MESOIONIC PESTICIDES | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 2012-05-10 | — | — | US | disclosed |
| US-20100323887-A1 | MESOIONIC PESTICIDES | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 2010-12-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140187776-A1 | MIXTURES OF MESOIONIC PESTICIDES | DDT, C5, CBR3 | LMNA 2556/4885POLB 4120/4885RAB9A 2436/4885 |
| US-20100323887-A1 | MESOIONIC PESTICIDES | DDT, CHRM1, CHRM3 | LMNA 4228/4885POLB 4546/4885RAB9A 888/4885 |
| US-20120115722-A1 | MIXTURES OF MESOIONIC PESTICIDES | DDT, C5, CBR3 | LMNA 2556/4885POLB 4120/4885RAB9A 2436/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.