SCHEMBL10246306

SCHEMBL10246306

CC(C)(C)Cc1cnc(Br)s1

nearest known ligand 0.43

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
▸ LMNA P02545 1/20 0.31
▸ POLB P06746 1/20 0.31
▸ RAB9A P51151 1/20 0.31
▸ ATM Q13315 1/20 0.31
▸ L3MBTL1 Q9Y468 1/20 0.31
▸ EPHX2 P34913 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27213267 0.83 — —
SCHEMBL1911594 0.80 SLC6A3 (0.40) LMNAPOLBRAB9AATML3MBTL1
SCHEMBL21325317 0.80 RAB9A (0.32) LMNAPOLBRAB9AATML3MBTL1
SCHEMBL4548402 0.79 PDK1 (0.33) —
SCHEMBL1912687 0.78 L3MBTL1 (0.49) LMNAPOLBRAB9AATML3MBTL1
SCHEMBL11922170 0.77 SLC6A3 (0.45) LMNAPOLBRAB9AATML3MBTL1
SCHEMBL13010776 0.77 LMNA (0.30) LMNAPOLBRAB9AATML3MBTL1
SCHEMBL3072164 0.75 — —
SCHEMBL4548405 0.74 SMN1; SMN2 (0.43) LMNA
SCHEMBL1911586 0.74 — —

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9314025-B2 Mixtures of mesoionic pesticides E I DU PONT DE NEMOURS AND COMPANY (US) 2016-04-19 — — US disclosed
US-9018220-B2 Mesoionic pesticides E I DU PONT DE NEMOURS AND COMPANY (US) 2015-04-28 — — US disclosed
US-20140187776-A1 MIXTURES OF MESOIONIC PESTICIDES E I DU PONT DE NEMOURS AND COMPANY (US) 2014-07-03 — — US disclosed
US-8552007-B2 Mesoionic pesticides E.I. DU PONT DE NEMOURS AND COMPANY (US) 2013-10-08 — — US disclosed
US-20120115722-A1 MIXTURES OF MESOIONIC PESTICIDES E. I. DU PONT DE NEMOURS AND COMPANY (US) 2012-05-10 — — US disclosed
US-20100323887-A1 MESOIONIC PESTICIDES E.I. DU PONT DE NEMOURS AND COMPANY (US) 2010-12-23 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20140187776-A1 MIXTURES OF MESOIONIC PESTICIDES DDT, C5, CBR3 LMNA 2556/4885POLB 4120/4885RAB9A 2436/4885
US-20100323887-A1 MESOIONIC PESTICIDES DDT, CHRM1, CHRM3 LMNA 4228/4885POLB 4546/4885RAB9A 888/4885
US-20120115722-A1 MIXTURES OF MESOIONIC PESTICIDES DDT, C5, CBR3 LMNA 2556/4885POLB 4120/4885RAB9A 2436/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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