Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRA1 | P14867 | 10/20 | 0.59 |
| ▸ | GABRB2 | P47870 | 10/20 | 0.59 |
| ▸ | GABRP | O00591 | 5/20 | 0.59 |
| ▸ | GABRD | O14764 | 5/20 | 0.59 |
| ▸ | GABRB1 | P18505 | 5/20 | 0.59 |
| ▸ | GABRG2 | P18507 | 5/20 | 0.59 |
| ▸ | GABRB3 | P28472 | 5/20 | 0.59 |
| ▸ | GABRA5 | P31644 | 5/20 | 0.59 |
| ▸ | GABRA3 | P34903 | 5/20 | 0.59 |
| ▸ | GABRA2 | P47869 | 5/20 | 0.59 |
| ▸ | GABRA4 | P48169 | 5/20 | 0.59 |
| ▸ | GABRE | P78334 | 5/20 | 0.59 |
| ▸ | GABRA6 | Q16445 | 5/20 | 0.59 |
| ▸ | GABRG1 | Q8N1C3 | 5/20 | 0.59 |
| ▸ | GABRG3 | Q99928 | 5/20 | 0.59 |
| ▸ | GABRQ | Q9UN88 | 5/20 | 0.59 |
| ▸ | PTGIR | P43119 | 2/20 | 0.52 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.49 |
| ▸ | TSHR | P16473 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17261550 | 0.90 | GABRP (0.51) | GABRA1GABRB2GABRPGABRDGABRB1 | |
| SCHEMBL415468 | 0.87 | GABRA1 (0.47) | GABRA1GABRB2GABRPGABRDGABRB1 | |
| SCHEMBL415236 | 0.83 | GABRA1 (0.65) | GABRA1GABRB2GABRPGABRDGABRB1 | |
| SCHEMBL10247836 | 0.82 | ALDH1A1 (0.55) | GABRA1GABRB2GABRPGABRDGABRB1 | |
| SCHEMBL10439184 | 0.81 | KMT2A (0.47) | GABRA1GABRB2GABRPGABRDGABRB1 | |
| SCHEMBL17274168 | 0.81 | KDM4E (0.58) | HSD17B10KDM4ETSHRKMT2ACYP1A2 | |
| SCHEMBL5206196 | 0.80 | KMT2A (0.48) | GABRA1GABRB2GABRPGABRDGABRB1 | |
| Methane SCHEMBL11623540 | 0.79 | KMT2A (0.47) | GABRA1GABRB2GABRPGABRDGABRB1 | |
| SCHEMBL17261567 | 0.79 | KMT2A (0.52) | GABRA1GABRB2GABRPGABRDGABRB1 | |
| SCHEMBL13361953 | 0.79 | PTGIR (0.53) | GABRA1GABRB2GABRPGABRDGABRB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120022054-A1 | NOVEL SUBSTITUTED ARYL DERIVATIVES, THEIR PROCESS OF PREPARATION AND THEIR THERAPEUTICAL USES AS ANTI-HIV AGENTS | LABORATOIRE BIODIM (FR) | 2012-01-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120022054-A1 | NOVEL SUBSTITUTED ARYL DERIVATIVES, THEIR PROCESS OF PREPARATION AND THEIR THERAPEUTICAL USES AS ANTI-HIV AGENTS | HAVCR2, MAVS, EIF2AK2 | GABRA1 3384/4885GABRB2 3283/4885GABRP 3362/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.