SCHEMBL102532

SCHEMBL102532

OB(O)c1ccc(N2CCOCC2)cc1

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 1/20 0.52
MAPT P10636 6/20 0.52
ALDH1A1 P00352 4/20 0.52
MEN1 O00255 3/20 0.52
KMT2A Q03164 3/20 0.52
HTT P42858 2/20 0.52
NPC1 O15118 2/20 0.52
RAB9A P51151 2/20 0.52
CYP1A2 P05177 1/20 0.52
KDM4E B2RXH2 3/20 0.52
ALOX15 P16050 2/20 0.52
HSD17B10 Q99714 2/20 0.52
HPGD P15428 1/20 0.52
USP2 O75604 1/20 0.50
TP53 P04637 1/20 0.50
MAPK1 P28482 1/20 0.50
PRKDC P78527 2/20 0.49
PKM P14618 2/20 0.49
PIK3CD O00329 1/20 0.49
PIK3CA P42336 1/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28377534 0.89 ALDH1A1 (0.46) LMNAMAPTALDH1A1MEN1KMT2A
SCHEMBL17121096 0.84 ALDH1A1 (0.52) LMNAMAPTALDH1A1MEN1KMT2A
SCHEMBL578242 0.83 L3MBTL3 (0.54) ALDH1A1KDM4E
SCHEMBL381631 0.83 ALDH1A1 (0.48) LMNAMAPTALDH1A1MEN1KMT2A
SCHEMBL9093746 0.82 LMNA (0.71) LMNAMAPTALDH1A1MEN1KMT2A
SCHEMBL1745699 0.81 ALDH1A1 (0.52) LMNAMAPTALDH1A1MEN1KMT2A
SCHEMBL10317320 0.81 ALDH1A1 (0.52) LMNAMAPTALDH1A1MEN1KMT2A
Hydrochloric Acid SCHEMBL27043157 0.81 ALDH1A1 (0.52) LMNAMAPTALDH1A1MEN1KMT2A
SCHEMBL875323 0.80 KMO (0.55) LMNAMAPTALDH1A1MEN1KMT2A
Hydrochloric Acid SCHEMBL1954079 0.79 ALDH1A1 (0.55) LMNAMAPTALDH1A1MEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 859 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-122079924-A Camphoryl benzothiazole ratio type fluorescent probe for detecting hydrazine and preparation method and application thereof 2026-05-26 CN claimed
CN-122079924-A Camphoryl benzothiazole ratio type fluorescent probe for detecting hydrazine and preparation method and application thereof 2026-05-26 CN disclosed
CN-122079924-A Camphoryl benzothiazole ratio type fluorescent probe for detecting hydrazine and preparation method and application thereof 2026-05-26 CN disclosed
EP-4745117-A1 NOVEL INDENONE DERIVATIVE AND USE THEREOF Amyloid Solution Inc. (KR) 2026-05-20 EP disclosed
CN-121673249-A Fluorescent emission material and preparation method thereof 阜阳欣奕华制药科技有限公司 2026-03-17 CN disclosed
US-12552801-B2 Indazole derivatives HOFFMANN-LA ROCHE INC. (US) 2026-02-17 US disclosed
EP-4692072-A1 PHOTOCHROMIC COMPOUND, PROPARGYL ALCOHOL COMPOUND, CURABLE COMPOSITION, OPTICAL ARTICLE, LENS, AND SPECTACLES TOKUYAMA CORPORATION (JP) 2026-02-11 EP disclosed
WO-2025264954-A1 PHARMACEUTICAL COMPOUNDS FOR THE TREATMENT OF COMPLEMENT MEDIATED DISORDERS ALEXION PHARMACEUTICALS, INC. (US) 2025-12-26 WO disclosed
EP-4663630-A1 NOVEL BENZIMIDAZOLONE DERIVATIVE COMPOUND AS AUTOTAXIN INHIBITOR LG Chem, Ltd. (KR) 2025-12-17 EP disclosed
EP-4655288-A1 PHD INHIBITORS Oxford University Innovation Limited (GB) 2025-12-03 EP disclosed
US-20040014755-A1 Rho-kinase inhibitors BAYER SCHERING PHARMA AKTIENGESELLSCHAFT (DE) 2004-01-22 US disclosed
WO-2003104227-A1 2-HETEROARYL CARBOXAMIDES BAYER HEALTHCARE AG (DE) 2003-12-18 WO disclosed
WO-2003078431-A1 AZA-BICYCLIC N-BIARYLAMIDES WITH AFFINITY FOR THE ALPHA-7 NICOTINIC ACETYLCHOLINE RECEPTOR BAYER HEALTHCARE AG (DE) 2003-09-25 WO disclosed
WO-2003059913-A1 ROH-KINASE INHIBITORS BAYER HEALTHCARE AG (DE) 2003-07-24 WO disclosed
EP-0832082-B1 N-HETEROARYL-PYRIDINESULFONAMIDE DERIVATIVES AND THEIR USE AS ENDOTHELIN ANTAGONISTS ASTRAZENECA AB (SE) 2001-11-21 EP disclosed
US-6258817-B1 PRODRUGS, HYPOTENSIVE AGENTS AND CARDIOVASCULAR DISORDERS ZENECA LTD. (GB) 2001-07-10 US disclosed
US-6060475-A Substituted pyrazin-2-yl-sulphonamide-(3-pyridyl) compounds and uses thereof ZENECA LIMITED (GB) 2000-05-09 US disclosed
US-5866568-A ENDOTHELIN RECEPTOR ANTAGONIST ACTIVITY ZENECA LIMITED (GB) 1999-02-02 US disclosed
EP-0832082-A1 N-HETEROARYL-PYRIDINESULFONAMIDE DERIVATIVES AND THEIR USE AS ENDOTHELIN ANTAGONISTS ZENECA LIMITED (GB) 1998-04-01 EP disclosed
WO-1996040681-A1 N-HETEROARYL-PYRIDINESULFONAMIDE DERIVATIVES AND THEIR USE AS ENDOTHELIN ANTAGONISTS ZENECA LIMITED (GB) 1996-12-19 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20040014755-A1 Rho-kinase inhibitors CIT, ROCK1, ROCK2 LMNA 3659/4885MAPT 2039/4885ALDH1A1 3561/4885
US-12552801-B2 Indazole derivatives EGFR, ABL1, ERBB3 LMNA 4809/4885MAPT 3358/4885ALDH1A1 1341/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.