Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | FDPS | P14324 | 1/20 | 0.33 |
| ▸ | BLM | P54132 | 1/20 | 0.32 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.31 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.31 |
| ▸ | CDC25B | P30305 | 1/20 | 0.31 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2887373 | 0.77 | ALDH1A1 (0.35) | FDPS | |
| SCHEMBL14154955 | 0.74 | OPRM1 (0.44) | MEN1KMT2AFDPSOPRM1 | |
| SCHEMBL2483429 | 0.72 | ALDH1A1 (0.38) | FDPS | |
| SCHEMBL10263861 | 0.70 | MEN1 (0.39) | MEN1CYP3A4ALOX15KMT2ALMNA | |
| SCHEMBL13061540 | 0.70 | LMNA (0.54) | MEN1CYP3A4ALOX15KMT2ALMNA | |
| SCHEMBL9065957 | 0.68 | OPRM1 (0.42) | OPRM1 | |
| SCHEMBL24504143 | 0.68 | FDPS (0.32) | FDPS | |
| SCHEMBL25057512 | 0.68 | MEN1 (0.56) | MEN1CYP3A4ALOX15KMT2ALMNA | |
| SCHEMBL1564304 | 0.68 | — | — | |
| SCHEMBL23904875 | 0.68 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2404890-A1 | Hydroxyl compounds and compositions for cholesterol management and related uses | Esperion Therapeutics Inc. (US) | 2012-01-11 | — | — | EP | disclosed |