Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CRHR1 | P34998 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12921206 | 0.87 | CRHR1 (0.32) | CRHR1 | |
| SCHEMBL186581 | 0.86 | CCR1 (0.35) | — | |
| SCHEMBL10266442 | 0.86 | TLR8 (0.33) | — | |
| SCHEMBL591223 | 0.82 | TLR8 (0.32) | CRHR1 | |
| SCHEMBL973013 | 0.79 | HTR2A (0.31) | — | |
| SCHEMBL973495 | 0.78 | PDE4D (0.35) | — | |
| SCHEMBL8064967 | 0.77 | DRD2 (0.39) | — | |
| SCHEMBL12921203 | 0.76 | ALDH1A1 (0.32) | — | |
| SCHEMBL187793 | 0.76 | CCR1 (0.34) | — | |
| SCHEMBL7708685 | 0.76 | CCR1 (0.34) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2215092-B1 | SUBSTITUTED PIPERIDINO-DIHYDROTHIENOPYRIMIDINES | BOEHRINGER INGELHEIM INT (DE) | 2012-01-25 | — | — | EP | disclosed |