SCHEMBL1027079

SCHEMBL1027079

CS(=O)(=O)O.O=C1CCC(O)C(=O)N1

nearest known ligand 0.39

Known targets — ChEMBL curated mechanism

ABL1ADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB2AGTR1BCL2BCL2A1BCL2L1BCL2L10BCL2L2BCRBRAFCHRM1CHRNA10CHRNA9DRD1DRD2DRD3DRD4DRD5EGFRF2FLT1FLT4GCKGHSRGNRHRGRIN1GRIN2AGRIN2BGRIN2CGRIN2DGRIN3AGRIN3BHTR1AHTR1BHTR1DHTR2AHTR2CHTR3AIDH2KDRKITMAOBMCL1MTTPPP4HBPDGFRBPIK3CAPIK3CBPIK3CDPIK3CGPIK3R1PIK3R2PIK3R3PIK3R5PIKFYVEROCK1ROCK2SLC18A2SLC6A2SLC6A3SLC6A4TACR1TUBA1ATUBA1BTUBA1CTUBA3CTUBA3ETUBA4ATUBBTUBB1TUBB2ATUBB2BTUBB3TUBB4ATUBB4BTUBB6TUBB8gyrAgyrBparCparEpol

The experimentally established mechanism targets of None. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
CRBN Q96SW2 20/20 0.39
DDB1 Q16531 15/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16447375 0.88
SCHEMBL5031751 0.88
SCHEMBL1028532 0.80 MAP3K14 (0.40) CRBN
SCHEMBL113961 0.79 CRBN (0.54) CRBNDDB1
SCHEMBL28863683 0.75 CRBN (0.46) CRBNDDB1
Succinimide SCHEMBL216817 0.74 CRBN (0.61) CRBNDDB1
SCHEMBL25905416 0.72 CRBN (0.51) CRBNDDB1
SCHEMBL27293791 0.72 CRBN (0.47) CRBNDDB1
SCHEMBL1027078 0.72 CRBN (0.50) CRBNDDB1
Sulfuric Acid SCHEMBL4970729 0.71 MAP3K14 (0.43) CRBN

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2016060856-A1 DISPERSED CARBON-COATED METAL PARTICLES, ARTICLES AND USES EASTMAN KODAK COMPANY (US) 2016-04-21 WO disclosed
WO-2015199988-A1 LATEX PRIMER COMPOSITION AND LATEX PRIMED SUBSTRATES EASTMAN KODAK COMPANY (US) 2015-12-30 WO disclosed
WO-2015134084-A1 PHOTOPOLYMERIZABLE COMPOSITIONS FOR ELECTROLESS PLATING METHODS EASTMAN KODAK COMPANY (US) 2015-09-11 WO disclosed
EP-2384457-A2 COATING COMPOSITIONS AZ Electronic Materials USA Corp. (US) 2011-11-09 EP disclosed
EP-2273968-A1 COMPOSITIONS AND METHODS INCORPORATING PHOTOCATALYSTS THE PROCTER & GAMBLE COMPANY (US) 2011-01-19 EP disclosed
WO-2010055406-A2 COATING COMPOSITIONS AZ ELECTRONIC MATERIALS USA CORP. (US) 2010-05-20 WO disclosed
WO-2009140076-A1 COMPOSITIONS AND METHODS INCORPORATING PHOTOCATALYSTS THE PROCTER & GAMBLE COMPANY (US) 2009-11-19 WO disclosed