SCHEMBL10270853

SCHEMBL10270853

CCOc1cc(C)nc2c1CCC/C2=N\OCCCO/N=C1\CCCc2ccc(C)nc21

nearest known ligand 0.31

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
LMNA P02545 1/20 0.30
MAPT P10636 1/20 0.30
HTT P42858 1/20 0.30
SMN1; SMN2 Q16637 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10271155 0.87 LMNA (0.31) LMNAMAPTHTTSMN1; SMN2
SCHEMBL10271160 0.84 L3MBTL1 (0.34) LMNAMAPTHTTSMN1; SMN2
SCHEMBL10270630 0.84 L3MBTL1 (0.31)
SCHEMBL10271158 0.81 NPY5R (0.33) LMNAMAPTHTT
SCHEMBL15771049 0.79 L3MBTL1 (0.32)
SCHEMBL10270991 0.79 L3MBTL1 (0.32)
SCHEMBL10271138 0.78 RAB9A (0.33) LMNAMAPT
SCHEMBL10270856 0.78 L3MBTL1 (0.36) LMNAMAPT
SCHEMBL10270628 0.77
SCHEMBL10270854 0.77 BCHE (0.35) LMNAMAPTHTTSMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20140162980-A1 NOVEL MICROBIOCIDAL DIOXIME ETHER DERIVATIVES SYNGENTA CROP PROTECTION LLC (US) 2014-06-12 US disclosed
US-20140162980-A1 NOVEL MICROBIOCIDAL DIOXIME ETHER DERIVATIVES SYNGENTA CROP PROTECTION LLC (US) 2014-06-12 US disclosed
WO-2012013754-A1 NOVEL MICROBIOCIDAL DIOXIME ETHER DERIVATIVES SYNGENTA PARTICIPATIONS AG (CH) 2012-02-02 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20140162980-A1 NOVEL MICROBIOCIDAL DIOXIME ETHER DERIVATIVES PRDX4, PRDX6, DDT LMNA 4570/4885MAPT 4671/4885HTT 4816/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.