Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ERCC1 | P07992 | 2/20 | 0.49 |
| ▸ | ERCC5 | P28715 | 2/20 | 0.49 |
| ▸ | FEN1 | P39748 | 2/20 | 0.49 |
| ▸ | ERCC4 | Q92889 | 2/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | ADRA1B | P35368 | 2/20 | 0.40 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.40 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.36 |
| ▸ | CDC7 | O00311 | 1/20 | 0.36 |
| ▸ | MAPK13 | O15264 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6510464 | 0.86 | ALDH1A1 (0.59) | ERCC1ERCC5FEN1ERCC4ALDH1A1 | |
| SCHEMBL6518727 | 0.82 | FEN1 (0.47) | ERCC1ERCC5FEN1ERCC4ALDH1A1 | |
| SCHEMBL2733484 | 0.82 | ERCC1 (0.50) | ERCC1ERCC5FEN1ERCC4ALDH1A1 | |
| SCHEMBL10272767 | 0.80 | ALDH1A1 (0.57) | ALDH1A1SMN1; SMN2HPGDLMNAHDAC1 | |
| SCHEMBL2759479 | 0.75 | ERCC1 (0.58) | ERCC1ERCC5FEN1ERCC4ALDH1A1 | |
| SCHEMBL24570832 | 0.74 | PARG (0.48) | ERCC1ERCC5FEN1ERCC4ALDH1A1 | |
| SCHEMBL2773897 | 0.72 | ADORA2B (0.59) | ERCC1ERCC5FEN1ERCC4ALDH1A1 | |
| SCHEMBL210872 | 0.72 | HDAC1 (0.74) | SMN1; SMN2LMNAHDAC1MAPTPOLB | |
| SCHEMBL3457587 | 0.69 | ERCC1 (0.45) | ERCC1ERCC5FEN1ERCC4ALDH1A1 | |
| SCHEMBL24570158 | 0.69 | PARG (0.49) | ERCC1ERCC5FEN1ERCC4ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8088805-B2 | Inhibitors of histone deacetylase | METHYLGENE INC. (CA) | 2012-01-03 | — | — | US | disclosed |