Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AR | P10275 | 1/20 | 0.39 |
| ▸ | RARA | P10276 | 1/20 | 0.36 |
| ▸ | RARB | P10826 | 1/20 | 0.36 |
| ▸ | RARG | P13631 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.34 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.34 |
| ▸ | SIRT5 | Q9NXA8 | 1/20 | 0.34 |
| ▸ | NR3C2 | P08235 | 6/20 | 0.33 |
| ▸ | RXRA | P19793 | 2/20 | 0.33 |
| ▸ | CA12 | O43570 | 1/20 | 0.33 |
| ▸ | CA1 | P00915 | 1/20 | 0.33 |
| ▸ | CA2 | P00918 | 1/20 | 0.33 |
| ▸ | CA9 | Q16790 | 1/20 | 0.33 |
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.32 |
| ▸ | MMP2 | P08253 | 1/20 | 0.32 |
| ▸ | MMP9 | P14780 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10275638 | 0.78 | KCNH2 (0.36) | AR | |
| SCHEMBL10276004 | 0.69 | KCNH2 (0.37) | AR | |
| SCHEMBL10275809 | 0.69 | NR3C2 (0.39) | ARRARARARBRARGALDH1A1 | |
| SCHEMBL307426 | 0.66 | MAP4K4 (0.60) | ARMAP4K4RXRACA1CA2 | |
| Hydrochloric Acid SCHEMBL15939679 | 0.65 | MAP4K4 (0.59) | ARMAP4K4RXRACA1CA2 | |
| SCHEMBL10275578 | 0.65 | SIRT5 (0.40) | ARRARARARBRARGMAP4K4 | |
| SCHEMBL23037552 | 0.65 | CA2 (0.59) | ARRARBRARGALDH1A1MAP4K4 | |
| SCHEMBL216706 | 0.65 | CA2 (0.64) | ARRARBRARGALDH1A1MAP4K4 | |
| Terephthalic Acid SCHEMBL27298641 | 0.64 | ALDH1A1 (0.68) | ARRARBRARGALDH1A1MAP4K4 | |
| SCHEMBL10275694 | 0.63 | TDP2 (0.35) | ALDH1A1NR3C2CA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120178915-A1 | PYRIMIDINE DERIVATIVES AND ANALOGS, PREPARATION METHOD AND USE THEREOF | XU LIFENG (US) | 2012-07-12 | — | — | US | claimed |
| CN-103554111-A | Aromatic heterocyclic pyridine derivatives and analogs, and preparation method and application thereof | LIAONING LIFENG SCIENCE AND TECHNOLOGY DEV CO LTD | 2014-02-05 | — | — | CN | disclosed |
| CN-101671336-B | Aromatic heterocyclic pyrimidine derivative and analogue, preparation method and application thereof | LIAONING LIFENG SCIENCE AND TECHNOLOGY DEV CO LTD | 2013-11-13 | — | — | CN | disclosed |
| US-20120178915-A1 | PYRIMIDINE DERIVATIVES AND ANALOGS, PREPARATION METHOD AND USE THEREOF | XU LIFENG (US) | 2012-07-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120178915-A1 | PYRIMIDINE DERIVATIVES AND ANALOGS, PREPARATION METHOD AND USE THEREOF | TYMP, TYMS, ADORA3 | AR 3221/4885RARA 1915/4885RARB 2365/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.