SCHEMBL10277213

SCHEMBL10277213

N=C(N)NCCC[C@H](NC(=O)Cc1ccccc1)C(=O)O

nearest known ligand 0.53

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
C3AR1 Q16581 1/20 0.53
NPY1R P25929 1/20 0.48
CHRNA1 P02708 4/20 0.47
CHRNG P07510 4/20 0.47
CHRNB1 P11230 4/20 0.47
CHRND Q07001 4/20 0.47
ITGB3 P05106 2/20 0.47
ITGA2B P08514 2/20 0.47
SHMT1 P34896 1/20 0.47
GAA P10253 1/20 0.47
HPGD P15428 1/20 0.47
CNR2 P34972 4/20 0.46
ATM Q13315 1/20 0.46
GRIA1 P42261 1/20 0.45
CNR1 P21554 1/20 0.45
TRPV1 Q8NER1 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4407484 1.00 C3AR1 (0.53) C3AR1NPY1RCHRNA1CHRNGCHRNB1
Phenylalanine Amide SCHEMBL7535742 0.91 CHRNA1 (0.46) C3AR1NPY1RCHRNA1CHRNGCHRNB1
SCHEMBL30423373 0.85 NPY4R (0.47) NPY1RCHRNA1CHRNGCHRNB1CHRND
SCHEMBL8423661 0.85 CTSG (0.54) C3AR1NPY1RITGB3ITGA2B
SCHEMBL7786354 0.85 FOLH1 (0.49) C3AR1NPY1RITGB3SHMT1
SCHEMBL7786368 0.85 FOLH1 (0.49) C3AR1NPY1RITGB3SHMT1
SCHEMBL7535795 0.85 NPY4R (0.59) NPY1RCHRNA1CHRNGCHRNB1CHRND
SCHEMBL6801489 0.84 C3AR1 (0.61) C3AR1SHMT1HPGD
SCHEMBL7653534 0.83 GPR34 (0.57) C3AR1
SCHEMBL4650743 0.83 NPY1R (0.61) NPY1RCHRNA1CHRNGCHRNB1CHRND

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116370491-A Use of antisense oligonucleotides in treating coronavirus related diseases 北京瑞博开拓医药科技有限公司 2023-07-04 CN disclosed
US-10632171-B2 Melanocortin receptor-specific peptides PALATIN TECHNOLOGIES, INC. (US) 2020-04-28 US disclosed
US-20190216887-A1 Melanocortin Receptor-Specific Peptides PALATIN TECHNOLOGIES INC (US) 2019-07-18 US disclosed
US-10179804-B2 Melanocortin receptor-specific peptides PALATIN TECHNOLOGIES, INC. (US) 2019-01-15 US disclosed
US-20160318977-A1 Melanocortin Receptor-Specific Peptides PALATIN TECHNOLOGIES INC (US) 2016-11-03 US disclosed
US-9458201-B2 Melanocortin receptor-specific heptapeptides PALATIN TECHNOLOGIES, INC. (US) 2016-10-04 US disclosed
US-20140357575-A1 Melanocortin Receptor-Specific Heptapeptides PALATIN TECHNOLOGIES INC (US) 2014-12-04 US disclosed
US-8846601-B2 Melanocortin receptor-specific peptides PALATIN TECHNOLOGIES, INC. (US) 2014-09-30 US disclosed
US-20120178701-A1 Melanocortin Receptor-Specific Peptides PALATIN TECHNOLOGIES, INC. (US) 2012-07-12 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10179804-B2 Melanocortin receptor-specific peptides MC1R, MC3R, MC5R C3AR1 87/4885NPY1R 6/4885CHRNA1 341/4885
US-20140357575-A1 Melanocortin Receptor-Specific Heptapeptides MC5R, MC1R, MC3R C3AR1 122/4885NPY1R 6/4885CHRNA1 297/4885
US-20190216887-A1 Melanocortin Receptor-Specific Peptides MC1R, MC3R, MC4R C3AR1 100/4885NPY1R 6/4885CHRNA1 331/4885
US-20160318977-A1 Melanocortin Receptor-Specific Peptides MC1R, MC3R, MC5R C3AR1 87/4885NPY1R 6/4885CHRNA1 341/4885
US-10632171-B2 Melanocortin receptor-specific peptides MC1R, MC3R, MC4R C3AR1 100/4885NPY1R 6/4885CHRNA1 331/4885
US-20120178701-A1 Melanocortin Receptor-Specific Peptides MC1R, MC3R, MC5R C3AR1 87/4885NPY1R 6/4885CHRNA1 341/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.