SCHEMBL10277450

SCHEMBL10277450

Cc1ccc(C(=O)P(=O)(O)OC(=O)c2c(C)cccc2-c2ccccc2)cc1

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 4/20 0.41
L3MBTL1 Q9Y468 3/20 0.41
MAPK1 P28482 1/20 0.41
TDP1 Q9NUW8 1/20 0.41
NPC1 O15118 3/20 0.37
RAB9A P51151 3/20 0.37
MAPT P10636 2/20 0.37
SMN1; SMN2 Q16637 2/20 0.37
CYP1A2 P05177 1/20 0.37
CYP3A4 P08684 1/20 0.37
CYP2C9 P11712 1/20 0.37
CYP2C19 P33261 1/20 0.37
ALDH1A1 P00352 2/20 0.36
HTT P42858 1/20 0.36
CES2 O00748 1/20 0.36
CES1 P23141 1/20 0.36
FGFR1 P11362 1/20 0.35
FGFR2 P21802 1/20 0.35
FGFR4 P22455 1/20 0.35
FGFR3 P22607 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL779557 0.87 ALDH1A1 (0.40) LMNAL3MBTL1TDP1NPC1RAB9A
SCHEMBL10277744 0.85 HNF4A (0.40) LMNAL3MBTL1NPC1RAB9AMAPT
SCHEMBL10277487 0.81 L3MBTL1 (0.40) LMNAL3MBTL1MAPK1TDP1SMN1; SMN2
SCHEMBL10277486 0.79 HDAC7 (0.52) LMNAL3MBTL1MAPK1TDP1MAPT
SCHEMBL10277449 0.77 PTPN5 (0.41) LMNAMAPTSMN1; SMN2CYP1A2CYP2C19
SCHEMBL779042 0.76 PTK2B (0.39) LMNATDP1NPC1RAB9AMAPT
SCHEMBL4827133 0.72 HTT (0.58) LMNAMAPK1TDP1RAB9AMAPT
SCHEMBL778488 0.72 AKR1C3 (0.41) LMNAL3MBTL1MAPK1TDP1NPC1
SCHEMBL779313 0.72 HPGD (0.39) LMNAL3MBTL1NPC1RAB9AMAPT
SCHEMBL2390011 0.71 FGFR1 (0.43) LMNAL3MBTL1NPC1RAB9AMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9343777-B2 Non-aqueous liquid electrolyte and non-aqueous liquid electrolyte secondary battery MITSUBISHI CHEMICAL CORPORATION (JP) 2016-05-17 US disclosed
US-20120177988-A1 NON-AQUEOUS LIQUID ELECTROLYTE AND NON-AQUEOUS LIQUID ELECTROLYTE SECONDARY BATTERY MITSUBISHI CHEMICAL CORPORATION (JP) 2012-07-12 US disclosed