Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.61 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.61 |
| ▸ | MCL1 | Q07820 | 3/20 | 0.61 |
| ▸ | MEN1 | O00255 | 3/20 | 0.61 |
| ▸ | APEX1 | P27695 | 2/20 | 0.61 |
| ▸ | THRB | P10828 | 2/20 | 0.61 |
| ▸ | RECQL | P46063 | 2/20 | 0.61 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.61 |
| ▸ | USP2 | O75604 | 1/20 | 0.61 |
| ▸ | POLB | P06746 | 1/20 | 0.61 |
| ▸ | PKM | P14618 | 1/20 | 0.61 |
| ▸ | BLM | P54132 | 1/20 | 0.61 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.53 |
| ▸ | GFER | P55789 | 1/20 | 0.53 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.53 |
| ▸ | BCL2A1 | Q16548 | 1/20 | 0.53 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.50 |
| ▸ | TSHR | P16473 | 2/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.50 |
| ▸ | GLA | P06280 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1143102 | 0.93 | KDM4E (0.61) | MAPTKMT2AMCL1MEN1APEX1 | |
| SCHEMBL9198998 | 0.86 | KEAP1 (0.66) | MAPTKMT2AMCL1MEN1APEX1 | |
| SCHEMBL4952867 | 0.86 | TSHR (0.50) | MAPTKMT2AMCL1MEN1APEX1 | |
| SCHEMBL1027768 | 0.80 | ALDH1A1 (0.54) | MAPTKMT2AMCL1MEN1APEX1 | |
| SCHEMBL20718934 | 0.79 | CYP3A4 (0.47) | MAPTKMT2AMCL1MEN1APEX1 | |
| SCHEMBL107833 | 0.78 | KMT2A (0.95) | MAPTKMT2AMCL1MEN1APEX1 | |
| SCHEMBL3978328 | 0.78 | MCL1 (0.65) | MAPTKMT2AMCL1MEN1APEX1 | |
| SCHEMBL3941969 | 0.77 | KDM4E (0.52) | MAPTKMT2AMCL1MEN1APEX1 | |
| Hydrochloric Acid SCHEMBL864766 | 0.77 | KMT2A (1.00) | MAPTKMT2AMCL1MEN1APEX1 | |
| SCHEMBL22336405 | 0.77 | APEX1 (0.67) | KMT2AMCL1MEN1APEX1TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102036952-A | Bis-aryl compounds for use as medicaments | BIOLIPOX AB | 2011-04-27 | — | — | CN | disclosed |
| US-20110071197-A1 | BIS-ARYL COMPOUNDS FOR USE AS MEDICAMENTS | BIOLIPOX AB (LV) | 2011-03-24 | — | — | US | disclosed |
| EP-2274280-A2 | BIS-ARYL COMPOUNDS FOR USE AS MEDICAMENTS | Biolipox AB (SE) | 2011-01-19 | — | — | EP | disclosed |
| WO-2009127822-A2 | BIS-ARYL COMPOUNDS FOR USE AS MEDICAMENTS | BIOLIPOX AB (SE) | 2009-10-22 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110071197-A1 | BIS-ARYL COMPOUNDS FOR USE AS MEDICAMENTS | LTC4S, LTB4R2, LTB4R | MAPT 4587/4885KMT2A 3849/4885MCL1 2428/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.