Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F10 | P00742 | 13/20 | 0.34 |
| ▸ | F2 | P00734 | 4/20 | 0.34 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.32 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.32 |
| ▸ | HTR1A | P08908 | 1/20 | 0.30 |
| ▸ | DRD2 | P14416 | 1/20 | 0.30 |
| ▸ | DRD3 | P35462 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11888214 | 0.83 | HTR1A (0.33) | F10F2HRH4HRH3HTR1A | |
| SCHEMBL4089034 | 0.77 | F10 (0.59) | F10F2HRH4HRH3 | |
| SCHEMBL4089036 | 0.77 | F10 (0.59) | F10F2HRH4HRH3 | |
| SCHEMBL10280029 | 0.72 | CCR1 (0.39) | — | |
| SCHEMBL11888244 | 0.72 | F10 (0.65) | F10F2 | |
| SCHEMBL764562 | 0.70 | RAB9A (0.47) | — | |
| SCHEMBL742520 | 0.66 | HRH4 (0.44) | F10F2HRH4HRH3 | |
| SCHEMBL12507535 | 0.65 | F10 (0.68) | F10F2 | |
| SCHEMBL12507710 | 0.65 | STS (0.41) | F10 | |
| SCHEMBL765153 | 0.63 | F10 (0.56) | F10F2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2431370-A1 | Monoacylated 1,2-diaminocycloalkanes | DAIICHI PHARMACEUTICAL CO., LTD. (JP) | 2012-03-21 | — | — | EP | disclosed |