Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.57 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.57 |
| ▸ | POLB | P06746 | 2/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.52 |
| ▸ | HTT | P42858 | 1/20 | 0.52 |
| ▸ | PKM | P14618 | 1/20 | 0.51 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.46 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.40 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 3/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10113389 | 0.84 | LMNA (0.80) | LMNAL3MBTL1POLBALDH1A1SMN1; SMN2 | |
| SCHEMBL10113509 | 0.81 | LMNA (0.62) | LMNAL3MBTL1POLBALDH1A1SMN1; SMN2 | |
| SCHEMBL10113653 | 0.73 | LMNA (1.00) | LMNAL3MBTL1POLBALDH1A1SMN1; SMN2 | |
| SCHEMBL13116159 | 0.70 | POLB (0.48) | LMNAPOLBALDH1A1SMN1; SMN2HTT | |
| SCHEMBL10113621 | 0.70 | LMNA (0.80) | LMNAL3MBTL1ALDH1A1SMN1; SMN2HTT | |
| SCHEMBL10113689 | 0.67 | KMT2A (0.66) | LMNAL3MBTL1POLBALDH1A1SMN1; SMN2 | |
| SCHEMBL10113298 | 0.67 | ALDH1A1 (0.65) | LMNAL3MBTL1POLBALDH1A1SMN1; SMN2 | |
| SCHEMBL7945527 | 0.66 | LMNA (0.47) | LMNAL3MBTL1ALDH1A1CYP3A4CYP2C9 | |
| SCHEMBL8438421 | 0.66 | LMNA (0.47) | LMNAL3MBTL1POLBALDH1A1SMN1; SMN2 | |
| SCHEMBL7210502 | 0.65 | ABCB11 (0.64) | LMNAL3MBTL1POLBALDH1A1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120046305-A1 | METHODS AND COMPOSITIONS FOR TREATING RESPIRATORY DISORDERS | ELI LILLY AND COMPANY | 2012-02-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120046305-A1 | METHODS AND COMPOSITIONS FOR TREATING RESPIRATORY DISORDERS | TRPA1, TRPV1, TRPV3 | LMNA 904/4885L3MBTL1 3252/4885POLB 3725/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.