⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12667819 | 0.75 | — | — | |
| SCHEMBL20153036 | 0.72 | CNR2 (0.39) | — | |
| SCHEMBL10793095 | 0.72 | — | — | |
| Bromide SCHEMBL4584444 | 0.70 | ALOX5 (0.44) | — | |
| Bromide SCHEMBL28524370 | 0.70 | ALOX5 (0.44) | — | |
| Water SCHEMBL9053915 | 0.70 | ALOX5 (0.44) | — | |
| SCHEMBL1755271 | 0.70 | — | — | |
| SCHEMBL14149244 | 0.68 | — | — | |
| SCHEMBL22284780 | 0.68 | — | — | |
| SCHEMBL22284791 | 0.68 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2102169-B1 | INDAZOLYL AMIDE DERIVATIVES FOR THE TREATMENT OF GLUCOCORTICOID RECEPTOR MEDIATED DISORDERS | ASTRAZENECA AB (SE) | 2012-06-20 | — | — | EP | disclosed |