Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR2 | P34972 | 3/20 | 0.39 |
| ▸ | CNR1 | P21554 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.38 |
| ▸ | HPGD | P15428 | 4/20 | 0.38 |
| ▸ | MAPT | P10636 | 3/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.38 |
| ▸ | GAA | P10253 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | ALDH2 | P05091 | 1/20 | 0.38 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.38 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.38 |
| ▸ | PPARG | P37231 | 1/20 | 0.38 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | PPARD | Q03181 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19847594 | 0.81 | MAOA (0.40) | ALDH1A1HPGDMAPTKDM4EMEN1 | |
| SCHEMBL20152983 | 0.79 | APP (0.39) | CNR2CNR1MAPTGAAMEN1 | |
| SCHEMBL12667819 | 0.79 | — | — | |
| SCHEMBL1755271 | 0.74 | — | — | |
| SCHEMBL12528430 | 0.72 | — | — | |
| SCHEMBL14149244 | 0.72 | — | — | |
| SCHEMBL14389831 | 0.72 | — | — | |
| SCHEMBL10280335 | 0.72 | — | — | |
| SCHEMBL8357372 | 0.72 | — | — | |
| SCHEMBL8197759 | 0.72 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210070787-A1 | Mito-Honokiol Compounds and Methods of Synthesis and Use Thereof | AIX-MARSEILLE UNIVERSITE (FR) | 2021-03-11 | — | — | US | disclosed |
| US-10836782-B2 | Mito-honokiol compounds and methods of synthesis and use thereof | THE MEDICAL COLLEGE OF WISCONSIN, INC. (US) | 2020-11-17 | — | — | US | disclosed |
| US-20180134737-A1 | MITO-HONOKIOL COMPOUNDS AND METHODS OF SYNTHESIS AND USE THEREOF | THE MEDICAL COLLEGE OF WISCONSIN, INC. | 2018-05-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180134737-A1 | MITO-HONOKIOL COMPOUNDS AND METHODS OF SYNTHESIS AND USE THEREOF | MFN2, MT-ND2, PCK2 | CNR2 2830/4885CNR1 3693/4885ALDH1A1 2874/4885 |
| US-20210070787-A1 | Mito-Honokiol Compounds and Methods of Synthesis and Use Thereof | CYP11B1, CYP11B2, MFN2 | CNR2 2552/4885CNR1 3367/4885ALDH1A1 2850/4885 |
| US-10836782-B2 | Mito-honokiol compounds and methods of synthesis and use thereof | MFN2, MT-ND2, PCK2 | CNR2 2830/4885CNR1 3693/4885ALDH1A1 2874/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.