SCHEMBL10280795

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL10280995	0.89	ILK (0.38)	ALOX5APFEN1S1PR1MAPTLMNA
	SCHEMBL11895332	0.87	POLB (0.33)	S1PR1ILKPOLB
	SCHEMBL16612971	0.87	SLC22A12 (0.33)	ALOX5APFEN1S1PR1ILKPOLB
	SCHEMBL14684625	0.84	NPC1 (0.33)	S1PR1MAPTLMNAILKNPC1
	SCHEMBL15426418	0.83	ALOX5AP (0.39)	ALOX5APFEN1MAPTLMNABCHE
	SCHEMBL29431663	0.82	POLB (0.34)	S1PR1ILKALDH1A1POLBSMN1; SMN2
	SCHEMBL14684606	0.82	POLB (0.34)	S1PR1ILKALDH1A1POLBSMN1; SMN2
	SCHEMBL15412820	0.82	ALOX5AP (0.37)	ALOX5APFEN1S1PR1MAPTLMNA
	SCHEMBL9952774	0.81	ILK (0.50)	ALOX5APFEN1MAPTLMNAILK
	SCHEMBL15426428	0.80	ILK (0.35)	ALOX5APFEN1S1PR1MAPTLMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.