SCHEMBL10280995

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL15426428	0.91	ILK (0.35)	ILKS1PR1DDR1AGPAT2LMNA
	SCHEMBL17609336	0.90	ILK (0.34)	ILKS1PR1DDR1LMNAMAPT
	SCHEMBL10280795	0.89	ALOX5AP (0.39)	ILKS1PR1DDR1POLBLMNA
	SCHEMBL11895332	0.87	POLB (0.33)	ILKS1PR1POLB
	SCHEMBL20708515	0.85	LMNA (0.41)	POLBLMNAMAPTKDM4EALDH1A1
	SCHEMBL14684606	0.85	POLB (0.34)	ILKS1PR1DDR1POLBKDM4E
	SCHEMBL29431663	0.85	POLB (0.34)	ILKS1PR1DDR1POLBKDM4E
	SCHEMBL16612971	0.84	SLC22A12 (0.33)	ILKS1PR1POLBDYRK1AALOX5AP
	SCHEMBL14684625	0.80	NPC1 (0.33)	ILKS1PR1POLBLMNAMAPT
	SCHEMBL10281006	0.79	MPL (0.44)	ILKS1PR1AGPAT2S1PR3KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.