Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.40 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.40 |
| ▸ | HTR2A | P28223 | 1/20 | 0.40 |
| ▸ | SCN1A | P35498 | 1/20 | 0.40 |
| ▸ | HTR2B | P41595 | 1/20 | 0.40 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.40 |
| ▸ | SCN2A | Q99250 | 1/20 | 0.40 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.40 |
| ▸ | SCN3A | Q9NY46 | 1/20 | 0.40 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20465874 | 0.96 | TSHR (0.49) | TSHRSMN1; SMN2KEAP1RAB9AMEN1 | |
| SCHEMBL111438 | 0.81 | TSHR (0.58) | TSHRSMN1; SMN2KEAP1ALDH1A1MAPK1 | |
| SCHEMBL16104624 | 0.81 | TSHR (0.44) | TSHRSMN1; SMN2KEAP1ALDH1A1MAPK1 | |
| SCHEMBL7106263 | 0.79 | TSHR (0.61) | TSHRSMN1; SMN2KEAP1ALDH1A1MAPK1 | |
| SCHEMBL5565860 | 0.78 | TSHR (0.49) | TSHRSMN1; SMN2KEAP1ALDH1A1MAPK1 | |
| SCHEMBL13086252 | 0.78 | TSHR (0.42) | TSHRSMN1; SMN2KEAP1RAB9AALDH1A1 | |
| SCHEMBL664660 | 0.78 | SMN1; SMN2 (0.48) | TSHRSMN1; SMN2KEAP1RAB9AALDH1A1 | |
| SCHEMBL27357923 | 0.77 | POLB (0.41) | MEN1KMT2AALDH1A1SIGMAR1 | |
| SCHEMBL18672765 | 0.77 | ALDH1A1 (0.44) | TSHRSMN1; SMN2KEAP1ALDH1A1MAPK1 | |
| SCHEMBL3387923 | 0.76 | ALDH1A1 (0.42) | TSHRSMN1; SMN2KEAP1RAB9AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20180223133-A1 | BIO-ELECTRODE COMPOSITION, BIO-ELECTRODE, METHOD FOR MANUFACTURING THE BIO-ELECTRODE, AND POLYMER COMPOUND | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 2018-08-09 | — | — | US | disclosed |
| EP-2602244-B1 | (Meth) Acrylic acid ester, activation energy ray curing composition, and inkjet recording ink | RICOH CO LTD (JP) | 2017-07-26 | — | — | EP | disclosed |
| US-20120041193-A1 | SUBSTITUTED INTERNAL VINYL-BORONIC ACIDS AND BORONIC ACID DERIVATIVES | FRONTIER SCIENTIFIC, INC. (US) | 2012-02-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120041193-A1 | SUBSTITUTED INTERNAL VINYL-BORONIC ACIDS AND BORONIC ACID DERIVATIVES | BLVRB, BTD, BCL6B | TSHR 1474/4885SMN1; SMN2 941/4885KEAP1 2633/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.