Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.38 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.38 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.38 |
| ▸ | HTR2A | P28223 | 1/20 | 0.38 |
| ▸ | SCN1A | P35498 | 1/20 | 0.38 |
| ▸ | HTR2B | P41595 | 1/20 | 0.38 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.38 |
| ▸ | SCN2A | Q99250 | 1/20 | 0.38 |
| ▸ | SCN3A | Q9NY46 | 1/20 | 0.38 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | USP2 | O75604 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3387923 | 0.85 | ALDH1A1 (0.42) | TSHRSMN1; SMN2KEAP1ALDH1A1MAPK1 | |
| SCHEMBL22313539 | 0.81 | KEAP1 (0.48) | TSHRSMN1; SMN2KEAP1ALDH1A1MAPK1 | |
| SCHEMBL63418 | 0.79 | TDP1 (0.46) | TSHRSMN1; SMN2KEAP1ALDH1A1MAPK1 | |
| SCHEMBL111438 | 0.78 | TSHR (0.58) | TSHRSMN1; SMN2KEAP1ALDH1A1MAPK1 | |
| SCHEMBL10282973 | 0.78 | TSHR (0.44) | TSHRSMN1; SMN2KEAP1ALDH1A1MAPK1 | |
| SCHEMBL63614 | 0.76 | TDP1 (0.47) | TSHRSMN1; SMN2KEAP1ALDH1A1MAPK1 | |
| SCHEMBL7106263 | 0.76 | TSHR (0.61) | TSHRSMN1; SMN2KEAP1ALDH1A1MAPK1 | |
| SCHEMBL20465874 | 0.75 | TSHR (0.49) | TSHRSMN1; SMN2KEAP1ALDH1A1MAPK1 | |
| SCHEMBL664660 | 0.75 | SMN1; SMN2 (0.48) | TSHRSMN1; SMN2KEAP1ALDH1A1MAPK1 | |
| SCHEMBL16298599 | 0.74 | ALDH1A1 (0.51) | TSHRSMN1; SMN2KEAP1ALDH1A1MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010116063-A1 | ETHYLENE COPOLYMER WITH PEG, CATIONIC AND ANIONIC UNITS, COSMETIC COMPOSITION INCLUDING SAME AND TREATMENT METHOD | L'OREAL (FR) | 2010-10-14 | — | — | WO | disclosed |