SCHEMBL1028381

SCHEMBL1028381

C1=C(Cc2ccccc2)CC(Cc2ccccc2)=C1Cc1ccccc1

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CALM1 P0DP23 1/20 0.42
SORT1 Q99523 1/20 0.33
HTR2C P28335 2/20 0.33
HTR2B P41595 1/20 0.33
MAOA P21397 2/20 0.32
MAOB P27338 2/20 0.32
BCL2 P10415 1/20 0.32
BCL2L1 Q07817 1/20 0.32
LMNA P02545 1/20 0.32
CYP1A2 P05177 1/20 0.32
ADRA2A P08913 1/20 0.32
CYP2D6 P10635 1/20 0.32
TSHR P16473 1/20 0.32
ADRA2B P18089 1/20 0.32
ADRA2C P18825 1/20 0.32
ADRA1D P25100 1/20 0.32
ADRA1A P35348 1/20 0.32
ADRA1B P35368 1/20 0.32
TAAR1 Q96RJ0 1/20 0.32
ALDH1A1 P00352 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8093021 0.79 TP53 (0.40) CALM1SORT1MAOAMAOBLMNA
SCHEMBL8090890 0.75 TP53 (0.36) CALM1LMNATAAR1ALDH1A1LTA4H
SCHEMBL8087972 0.74 TLR7 (0.36) CALM1
SCHEMBL8087990 0.73 SIGMAR1 (0.35) CALM1
SCHEMBL8093000 0.73 SIGMAR1 (0.35) CALM1MAOACYP2D6TAAR1ALDH1A1
SCHEMBL5082503 0.72 ACHE (0.46) CALM1HTR2CHTR2BMAOAMAOB
SCHEMBL8087900 0.72 TP53 (0.40) CALM1SORT1MAOAMAOBLMNA
SCHEMBL8079473 0.69 CALM1 (0.35) CALM1SORT1MAOAMAOBTAAR1
SCHEMBL19102829 0.69 CALM1 (0.55) CALM1SORT1BCL2BCL2L1LMNA
SCHEMBL8088069 0.68 TAAR1 (0.37) CALM1SORT1MAOALMNACYP2D6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 31 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0993478-B2 OLEFIN POLYMERIZATION PROCESS BOREALIS TECH OY (FI) 2011-01-19 EP claimed
US-6921799-B1 Olefin polymerization process BOREALIS A/S (DK) 2005-07-26 US claimed
EP-0993478-B1 OLEFIN POLYMERIZATION PROCESS BOREALIS TECH OY (FI) 2004-04-07 EP claimed
EP-1261660-B2 PROCESS FOR ADDITION OF ADDITIVES TO POLYMER PARTICLES BOREALIS TECH OY (FI) 2012-11-21 EP disclosed
EP-0993478-B2 OLEFIN POLYMERIZATION PROCESS BOREALIS TECH OY (FI) 2011-01-19 EP disclosed
EP-1272559-B1 PROCESS FOR PRODUCING PROPYLENE BASED POLYMER COMPOSITIONS BOREALIS TECH OY (FI) 2008-11-26 EP disclosed
EP-1313561-B1 SUPPORTED CATALYST BOREALIS TECH OY (FI) 2006-04-05 EP disclosed
US-6995219-B2 Olefin polymerization process BOREALIS TECHNOLOGY OY (FI) 2006-02-07 US disclosed
US-6982238-B2 Supported catalyst BOREALIS TECHNOLOGY OY (FI) 2006-01-03 US disclosed
US-6921799-B1 Olefin polymerization process BOREALIS A/S (DK) 2005-07-26 US disclosed
EP-1385890-B1 OLEFIN POLYMERISATION PROCESS BOREALIS TECH OY (FI) 2005-07-20 EP disclosed
US-6627706-B1 Molecular weight control by monitoring hydrogen consumption; addition polymerization and catalysis using metallocene BOREALIS TECHNOLOGY OY (FI) 2003-09-30 US disclosed
US-20030176603-A1 Process for producing propylene based polymer compositions BOREALIS TECHNOLOGY OY (FI) 2003-09-18 US disclosed
US-20030166460-A1 Supported catalyst BOREALIS TECHNOLOGY OY (FI) 2003-09-04 US disclosed
US-6613851-B1 Cyclic carbene- eta -ligand complexes for catalysis of olefin polymerization. BOREALIS TECHNOLOGY OY (FI) 2003-09-02 US disclosed
US-6610799-B1 Consistent polymer product; particulate multisite catalysts or catalyst mixtures with rather small compositional differences between them using several feeders BOREALIS TECHNOLOGY OY (FI) 2003-08-26 US disclosed
US-20030146542-A1 Process for addition of additives to polymer particles BOREALIS TECHNOLOGY OY (FI) 2003-08-07 US disclosed
US-20030078340-A1 Impregnating a mechanically fluidized porous particulate support material with a catalyst and polymerizing monomer(s) to produce polymer; heating mixture antioxidants, ultraviolet radiation stabilizer, diluent and metal stearate; depositing BOREALIS TECHNOLOGY OY (FI) 2003-04-24 US disclosed
EP-1165622-B1 OLEFIN POLYMERISATION PROCESS BOREALIS TECH OY (FI) 2003-04-09 EP disclosed
EP-1114081-B1 POLYMER FOR ROTOMOULDING BOREALIS TECH OY (FI) 2002-10-09 EP disclosed