Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CALM1 | P0DP23 | 1/20 | 0.55 |
| ▸ | SORT1 | Q99523 | 1/20 | 0.44 |
| ▸ | BCL2 | P10415 | 1/20 | 0.39 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.39 |
| ▸ | TAAR1 | Q96RJ0 | 3/20 | 0.38 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.38 |
| ▸ | SLC18A2 | Q05940 | 1/20 | 0.38 |
| ▸ | LTA4H | P09960 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 3/20 | 0.38 |
| ▸ | IDO1 | P14902 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.38 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.38 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.38 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.38 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23189253 | 0.77 | PLA2G2A (0.49) | CALM1SORT1LTA4HTSHRLMNA | |
| SCHEMBL1923108 | 0.76 | CALM1 (0.58) | CALM1BCL2BCL2L1TAAR1SIGMAR1 | |
| SCHEMBL2502178 | 0.74 | SORT1 (0.45) | CALM1SORT1BCL2BCL2L1CYP1A2 | |
| Diphenylmethane SCHEMBL14763944 | 0.73 | CALM1 (1.00) | CALM1BCL2BCL2L1LTA4HTSHR | |
| Diphenylmethane SCHEMBL3792579 | 0.73 | CALM1 (1.00) | CALM1BCL2BCL2L1LTA4HTSHR | |
| Diphenylmethane SCHEMBL4361124 | 0.73 | CALM1 (1.00) | CALM1BCL2BCL2L1LTA4HTSHR | |
| Diphenylmethane SCHEMBL1303 | 0.73 | CALM1 (1.00) | CALM1BCL2BCL2L1LTA4HTSHR | |
| Diphenylmethane SCHEMBL28172316 | 0.73 | CALM1 (1.00) | CALM1BCL2BCL2L1LTA4HTSHR | |
| SCHEMBL20460272 | 0.72 | TSHR (0.54) | CALM1TAAR1SIGMAR1LTA4HTSHR | |
| SCHEMBL110859 | 0.72 | CALM1 (0.52) | CALM1BCL2BCL2L1TAAR1SIGMAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9701771-B2 | Substituted zirconocenes catalysts and methods of use in polymerization reactions | BASELL POLYOLEFINE GMBH (DE) | 2017-07-11 | — | — | US | disclosed |