Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SGMS2 | Q8NHU3 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
| ▸ | IDO1 | P14902 | 1/20 | 0.38 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.38 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 4/20 | 0.37 |
| ▸ | HTT | P42858 | 2/20 | 0.37 |
| ▸ | RAB9A | P51151 | 4/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.36 |
| ▸ | KDM4A | O75164 | 1/20 | 0.36 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 4/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.36 |
| ▸ | NPC1 | O15118 | 3/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | CRHBP | P24387 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11576066 | 1.00 | SGMS2 (0.43) | SGMS2HPGDIDO1GABRA1GABRB2 | |
| SCHEMBL9141059 | 0.78 | ALDH1A1 (0.51) | SGMS2HPGDGAAHTTRAB9A | |
| SCHEMBL104062 | 0.77 | IDO1 (0.59) | HPGDIDO1GABRA1GABRB2GAA | |
| SCHEMBL11578246 | 0.77 | SGMS2 (0.43) | SGMS2HPGDHTTRAB9AL3MBTL1 | |
| SCHEMBL11204634 | 0.76 | FPR1 (0.42) | HPGDGAAHTTMAPTKMT2A | |
| SCHEMBL2204567 | 0.75 | GABRA1 (0.43) | HPGDIDO1GABRA1GABRB2GAA | |
| SCHEMBL9141526 | 0.74 | ALDH1A1 (0.59) | SGMS2HPGDGAAHTTRAB9A | |
| SCHEMBL7689102 | 0.74 | SGMS2 (0.55) | SGMS2GAARAB9AL3MBTL1KDM4A | |
| SCHEMBL11575400 | 0.72 | KEAP1 (0.42) | GAAHTTRAB9AMAPTKMT2A | |
| SCHEMBL141473 | 0.71 | TDP1 (0.56) | SGMS2GAAL3MBTL1KDM4ETDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2274286-A1 | KERATIN DYEING COMPOUNDS, KERATIN DYEING COMPOSITIONS CONTAINING SAID COMPOUNDS, AND USE THEREOF | The Procter & Gamble Company (US) | 2011-01-19 | — | — | EP | disclosed |
| WO-2009140451-A1 | KERATIN DYEING COMPOUNDS, KERATIN DYEING COMPOSITIONS CONTAINING SAID COMPOUNDS, AND USE THEREOF | THE PROCTER & GAMBLE COMPANY (US) | 2009-11-19 | — | — | WO | disclosed |