Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATM | Q13315 | 1/20 | 0.55 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.47 |
| ▸ | PRKDC | P78527 | 1/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.47 |
| ▸ | ERN1 | O75460 | 3/20 | 0.44 |
| ▸ | PDE7A | Q13946 | 1/20 | 0.44 |
| ▸ | HSPB1 | P04792 | 2/20 | 0.41 |
| ▸ | ALDH5A1 | P51649 | 1/20 | 0.41 |
| ▸ | ABAT | P80404 | 1/20 | 0.41 |
| ▸ | VCAM1 | P19320 | 1/20 | 0.41 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.40 |
| ▸ | KCNMA1 | Q12791 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | TYMS | P04818 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL564611 | 0.85 | ATM (0.60) | ATMTDP1ALDH1A1MAPTKDM4E | |
| SCHEMBL29547124 | 0.85 | ATM (0.60) | ATMTDP1ALDH1A1MAPTKDM4E | |
| SCHEMBL12826254 | 0.83 | TDP1 (0.53) | ATMTDP1ALDH1A1MAPTCYP3A4 | |
| SCHEMBL14833771 | 0.83 | TDP1 (0.53) | ATMTDP1ALDH1A1MAPTPDE7A | |
| SCHEMBL14714243 | 0.80 | MAPT (0.53) | TDP1ALDH1A1MAPTKDM4ECYP3A4 | |
| SCHEMBL30657510 | 0.79 | ATM (0.49) | ATMTDP1ALDH1A1MAPTPDE7A | |
| SCHEMBL20338410 | 0.79 | ATM (0.49) | ATMTDP1ALDH1A1MAPTPDE7A | |
| SCHEMBL203753 | 0.78 | ERN1 (0.59) | TDP1ALDH1A1MAPTKDM4ECYP3A4 | |
| SCHEMBL10971487 | 0.78 | ALDH5A1 (0.65) | ALDH1A1MAPTKDM4ECYP3A4ALOX15 | |
| SCHEMBL1094404 | 0.78 | ALDH1A1 (0.56) | ATMTDP1ALDH1A1MAPTKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 171 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118239956-A | Preparation of 11-fluorocamptothecin derivative and application thereof in anti-tumor aspect | 兰州大学 | 2024-06-25 | — | — | CN | claimed |
| CN-107188851-B | Method for synthesizing astemizole key intermediate and derivative thereof | 湖南大学 | 2020-04-07 | — | — | CN | claimed |
| CN-107188851-A | A kind of method for synthesizing astemizole key intermediate and its derivative | 湖南大学 | 2017-09-22 | — | — | CN | claimed |
| US-20100034748-A1 | Molecular imaging probes based on loaded reactive nano-scale latex | QUANTUM MEDICAL HOLDINGS, LLC | 2010-02-11 | — | — | US | claimed |
| WO-2010016858-A2 | MOLECULAR IMAGING PROBES | CARESTREAM HEALTH, INC. (US) | 2010-02-11 | — | — | WO | claimed |
| JP-4270267-A | — | — | None | — | — | JP | disclosed |
| US-12630532-B2 | Indole-substituted quinolines and their combination with Plk1 inhibitors for the treatment of cancer | UNIVERSITY OF KENTUCKY RESEARCH FOUNDATION (US) | 2026-05-19 | — | — | US | disclosed |
| US-20260097034-A1 | METALLOENZYME INHIBITOR COMPOUNDS | CORXEL PHARMACEUTICALS HONG KONG LTD (HK) | 2026-04-09 | — | — | US | disclosed |
| EP-4703361-A1 | PYRIDAZINONE TRPC4/5 INHIBITOR AND USE THEREOF | Shanghai Institute of Materia Medica, Chinese Academy of Sciences (CN) | 2026-03-04 | — | — | EP | disclosed |
| US-20260027131-A1 | PRODRUGS, PRODRUG COMPOSITIONS AND RELATED METHODS | PRAESIDIA BIOTHERAPEUTICS INC (US) | 2026-01-29 | — | — | US | disclosed |
| US-12458642-B2 | Metalloenzyme inhibitor compounds | CORXEL PHARMACEUTICALS HONG KONG LIMITED (HK) | 2025-11-04 | — | — | US | disclosed |
| EP-4634169-A1 | 3-FLUORO-4-HYDROXYBENZMIDE-CONTAINING INHIBITORS AND/OR DEGRADERS AND USES THEREOF | Pfizer Inc. (US) | 2025-10-22 | — | — | EP | disclosed |
| EP-0128006-A2 | A soil-disease-controlling agent | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1984-12-12 | — | — | EP | disclosed |
| US-4446284-A | Method for preparing a polymer containing pendant unsaturation | THE GOODYEAR TIRE & RUBBER COMPANY (US) | 1984-05-01 | — | — | US | disclosed |
| US-4390693-A | BACTERICIDE | MERCK & CO., INC. (US) | 1983-06-28 | — | — | US | disclosed |
| US-4255423-A | BACTERICIDES | MERCK & CO., INC. (US) | 1981-03-10 | — | — | US | disclosed |
| US-4134981-A | ANTIALLERGENS | PFIZER INC. (US) | 1979-01-16 | — | — | US | disclosed |
| US-4120962-A | Fused pyrimidin-4(3H)-ones as antiallergy agents | PFIZER INC. (US) | 1978-10-17 | — | — | US | disclosed |
| US-4044134-A | FUSED WITH QUINOLINE OR PYRIDINE, 2-METHYL, ETHYL, OR ACETYL GROUP | PFIZER INC. (US) | 1977-08-23 | — | — | US | disclosed |
| US-3974161-A | Fused pyrimidin-4(3H)-ones as antiallergy agents | PFIZER INC. (US) | 1976-08-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12458642-B2 | Metalloenzyme inhibitor compounds | CYP11B2, CYP11B1, HSD11B2 | ATM 4026/4885TDP1 2721/4885ALDH1A1 232/4885 |
| US-20260027131-A1 | PRODRUGS, PRODRUG COMPOSITIONS AND RELATED METHODS | DNPEP, SLC7A1, SLC6A7 | ATM 3568/4885TDP1 1745/4885ALDH1A1 2225/4885 |
| US-20100034748-A1 | Molecular imaging probes based on loaded reactive nano-scale latex | CLTA, COPE, CD68 | ATM 1350/4885TDP1 987/4885ALDH1A1 2203/4885 |
| US-20260097034-A1 | METALLOENZYME INHIBITOR COMPOUNDS | CPN1, TPP1, DPP4 | ATM 4632/4885TDP1 692/4885ALDH1A1 189/4885 |
| US-12630532-B2 | Indole-substituted quinolines and their combination with Plk1 inhibitors for the treatment of cancer | PLK1, MYC, PLK4 | ATM 116/4885TDP1 1523/4885ALDH1A1 1529/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.